Evidence map›Paper›PMID 28661182›Full record

ArticleAmerican journal of respiratory and critical care medicine2017

Prenatal Nitrate Exposure and Childhood Asthma. Influence of Maternal Prenatal Stress and Fetal Sex.

Sonali Bose, Yueh-Hsiu Mathilda Chiu, Hsiao-Hsien Leon Hsu, Qian Di, Maria José Rosa, Alison Lee, Itai Kloog, Ander Wilson, Joel Schwartz, Robert O Wright and 3 more

Open access · greenAbstract read
In one paragraph

Article in American journal of respiratory and critical care medicine, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 35 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
35citing papers in PubMed, 1 pooled it
4.1field-weighted citation impact, top 6% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

35 citing papers in PubMed, 1 synthesis or guideline pooled it, 68 citations in OpenAlex.

  1. Pooled it
  2. Trial
  3. Review
  4. Article
  5. Article
  6. Article
  7. Article
  8. Review
  9. Article
  10. Effect of In utero Exposure to Air Pollution on Adulthood Hospitalizations.Journal of urban health : bulletin of the New York Academy of Medicine · 2024
    Review
  11. Article
  12. Article
  13. Article
  14. Article
  15. Article
  16. Article
  17. Article
  18. Maternal active asthma in pregnancy influences associations between polyunsaturated fatty acid intake and child asthma.Annals of allergy, asthma & immunology : official publication of the American College of Allergy, Asthma, & Immunology · 2021
    Article
  19. Article
  20. Article
4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

13 authors at 6 institutions in 2 countries.

Sonali Bose1 Division of Pulmonary and Critical Care Medicine.
Yueh-Hsiu Mathilda Chiu2 Department of Pediatrics.
Hsiao-Hsien Leon Hsu3 Department of Environmental Medicine and Public Health, and.
Qian Di4 Department of Environmental Health and.
Maria José Rosa3 Department of Environmental Medicine and Public Health, and.
Alison Lee1 Division of Pulmonary and Critical Care Medicine.
Itai Kloog5 Department of Geography and Environmental Development, Ben-Gurion University of the Negev, BeerSheba, Israel.
Ander Wilson6 Department of Statistics, Colorado State University, Fort Collins, Colorado; and.
Joel Schwartz4 Department of Environmental Health and.
Robert O Wright2 Department of Pediatrics.
Sheldon Cohen8 Department of Psychology, Carnegie Mellon University, Pittsburgh, Pennsylvania.
Brent A Coull9 Department of Biostatistics, Harvard T. H. Chan School of Public Health, Boston, Massachusetts.
Rosalind J Wright2 Department of Pediatrics.
Pediatrics and Genetics · USBen-Gurion University of the Negev · ILCarnegie Mellon University · USColorado State University · USHarvard University · USPulmonary and Critical Care Associates · US

Funding

Translational Research Support CoreP30ES000002 · NIEHS · HARVARD UNIVERSITY (SCH OF PUBLIC HLTH) · PI Marc G Weisskopf · 1985 to 2026
$44.6M
The Mount Sinai Transdisciplinary Center on Early Environmental ExposuresP30ES023515 · NIEHS · ICAHN SCHOOL OF MEDICINE AT MOUNT SINAI · PI Robert O Wright · 2014 to 2026
$21.3M
GRADUATE TRAINING IN BIOSTATISTICST32ES007142 · NIEHS · HARVARD UNIVERSITY (SCH OF PUBLIC HLTH) · PI Brent Andrew Coull · 1985 to 2026
$11.9M
Research Training Program in Pediatric ExposomicsT32HD049311 · NICHD · ICAHN SCHOOL OF MEDICINE AT MOUNT SINAI · PI KECIA Nicole CARROLL, Robert O Wright · 2007 to 2026
$7.4M
Stress, Environment, and Genetics in Urban AsthmaR01HL080674 · NHLBI · ICAHN SCHOOL OF MEDICINE AT MOUNT SINAI · PI WRIGHT, ROSALIND J · 2005 to 2014
$7.0M
MULTI-LEVEL ANALYSIS OF URBAN CHILDHOOD ASTHMA RISKR01ES010932 · NIEHS · BRIGHAM AND WOMEN'S HOSPITAL · PI WRIGHT, ROSALIND J · 2000 to 2004
$3.0M
Asthma Coalition on Community, Environment and StressU01HL072494 · NHLBI · BRIGHAM AND WOMEN'S HOSPITAL · PI WRIGHT, ROSALIND J · 2002 to 2003
$1.5M
Prenatal PM2.5 and programming of respiratory outcomes: Placental biomarkers and effect modification by stressK23HL135349 · NHLBI · ICAHN SCHOOL OF MEDICINE AT MOUNT SINAI · PI LEE, ALISON G · 2017 to 2021
$884k
NHLBI NIH HHS R01 HL080674NHLBI NIH HHS U01 HL072494NIEHS NIH HHS P30 ES000002NIEHS NIH HHS P30 ES023515NIEHS NIH HHS R01 ES010932NIEHS NIH HHS T32 ES007142
6 · The paper itself

Abstract

rationaleImpact of ambient pollution upon children's asthma may differ by sex, and exposure dose and timing. Psychosocial stress can also modify pollutant effects. These associations have not been examined for in utero ambient nitrate exposure.

objectivesWe implemented Bayesian-distributed lag interaction models to identify sensitive prenatal windows for the influence of nitrate (NO

methodsAnalyses included 752 mother-child dyads. Daily ambient NO MEASUREMENTS AND MAIN

resultsMost mothers were Hispanic (54%) or black (29%), had a high school education or less (66%), never smoked (80%), and reported low prenatal stress (58%); 15% of children developed asthma. BDILMs adjusted for maternal age, race, education, prepregnancy obesity, atopy, and smoking status identified two sensitive windows (7-19 and 33-40 wk gestation), during which increased NO

conclusionsPrenatal NO

Indexed as

AdultAir PollutionAsthmaBostonCausalityChild, PreschoolComorbidityFemaleHumansInfantMaleNitratesPregnancyPrenatal Exposure Delayed EffectsProspective StudiesSex FactorsNitratesair pollutionasthmanitrateprenatalsensitive window

Identifiers

PMID28661182
PMCPMC5736975
OpenAlexW2727722179

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.