ArticleHuman brain mapping2017
Pivotal role of hMT+ in long-range disambiguation of interhemispheric bistable surface motion.
Article in Human brain mapping, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 9 papers.
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9 citing papers in PubMed, 16 citations in OpenAlex.
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- Brain Hemispheric Asymmetry in Schizophrenia and Bipolar Disorder.Journal of clinical medicine · 2023Article
- Non-stimulated regions in early visual cortex encode the contents of conscious visual perception.Human brain mapping · 2022Article
- Task-based functional MRI challenges in clinical neuroscience: Choice of the best head motion correction approach in multiple sclerosis.Frontiers in neuroscience · 2022Article
- Changes in hemodynamic response function components reveal specific changes in neurovascular coupling in type 2 diabetes.Frontiers in physiology · 2022Article
- The dual nature of the BOLD signal: Responses in visual area hMT+ reflect both input properties and perceptual decision.Human brain mapping · 2021Article
- The role of the insula in intuitive expert bug detection in computer code: an fMRI study.Brain imaging and behavior · 2019Article
- Tracking perceptual decision mechanisms through changes in interhemispheric functional connectivity in human visual cortex.Scientific reports · 2019Article
- A Generic Mechanism for Perceptual Organization in the Parietal Cortex.The Journal of neuroscience : the official journal of the Society for Neuroscience · 2018Article
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4 authors at 1 institution in 1 country.
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No grant is acknowledged in the PubMed record.
Abstract
It remains an open question whether long-range disambiguation of ambiguous surface motion can be achieved in early visual cortex or instead in higher level regions, which concerns object/surface segmentation/integration mechanisms. We used a bistable moving stimulus that can be perceived as a pattern comprehending both visual hemi-fields moving coherently downward or as two widely segregated nonoverlapping component objects (in each visual hemi-field) moving separately inward. This paradigm requires long-range integration across the vertical meridian leading to interhemispheric binding. Our fMRI study (n = 30) revealed a close relation between activity in hMT+ and perceptual switches involving interhemispheric segregation/integration of motion signals, crucially under nonlocal conditions where components do not overlap and belong to distinct hemispheres. Higher signal changes were found in hMT+ in response to spatially segregated component (incoherent) percepts than to pattern (coherent) percepts. This did not occur in early visual cortex, unlike apparent motion, which does not entail surface segmentation. We also identified a role for top-down mechanisms in state transitions. Deconvolution analysis of switch-related changes revealed prefrontal, insula, and cingulate areas, with the right superior parietal lobule (SPL) being particularly involved. We observed that directed influences could emerge either from left or right hMT+ during bistable motion integration/segregation. SPL also exhibited significant directed functional connectivity with hMT+, during perceptual state maintenance (Granger causality analysis). Our results suggest that long-range interhemispheric binding of ambiguous motion representations mainly reflect bottom-up processes from hMT+ during perceptual state maintenance. In contrast, state transitions maybe influenced by high-level regions such as the SPL. Hum Brain Mapp 38:4882-4897, 2017. © 2017 Wiley Periodicals, Inc.
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