Article3 Biotech2017
Investigation of in vitro digestibility of dietary microalga Chlorella vulgaris and cyanobacterium Spirulina platensis as a nutritional supplement.
Article in 3 Biotech, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 26 papers.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
26 citing papers in PubMed, 92 citations in OpenAlex.
- Spirulina as a natural shield: a comprehensive review of its protective effects against lead toxicity.Archives of toxicology · 2025Review
- Microalgal and Cyanobacterial Biomasses Modified the Activity of Extracellular Products from Bacillus pumilus: An In Vitro and In Vivo Assessment.Probiotics and antimicrobial proteins · 2025Article
- Unleashing the power of microalgae: a pioneering path to sustainability and achieving the sustainable development goals.Environmental science and pollution research international · 2025Review
- Role of SimulatedNutrients · 2024Article
- Exploring Feed Digestibility and Broiler Performance in Response to Dietary Supplementation ofAnimals : an open access journal from MDPI · 2024Article
- Microalgae as an Alternative Mineral Source in Poultry Nutrition.Veterinary sciences · 2024Review
- Microalgae-Sustainable Source for Alternative Proteins and Functional Ingredients Promoting Gut and Liver Health.Global challenges (Hoboken, NJ) · 2023Review
- Alternative Protein Sources and Novel Foods: Benefits, Food Applications and Safety Issues.Nutrients · 2023Review
- Enhancing Digestibility ofAnimals : an open access journal from MDPI · 2023Review
- Perspective: Multiomics and Machine Learning Help Unleash the Alternative Food Potential of Microalgae.Advances in nutrition (Bethesda, Md.) · 2023Article
- Influence of magnesium concentrations on the biomass and biochemical variations in the freshwater algae,Heliyon · 2023Article
- The potentials and challenges of using fermentation to improve the sensory quality of plant-based meat analogs.Frontiers in microbiology · 2023Review
- The utility of algae as sources of high value nutritional ingredients, particularly for alternative/complementary proteins to improve human health.Frontiers in nutrition · 2023Review
- Digestive Constraints ofFoods (Basel, Switzerland) · 2022Review
- Supercritical COMolecules (Basel, Switzerland) · 2022Article
- Investigation of Bioavailability and Food-Processing Properties ofFoods (Basel, Switzerland) · 2022Article
- Article
- Bioactive Hydrolysates fromMolecules (Basel, Switzerland) · 2022Article
- Fermented Biomass ofAntioxidants (Basel, Switzerland) · 2022Article
- Impact of thermal processing on the nutrients, phytochemicals, and metal contaminants in edible algae.Critical reviews in food science and nutrition · 2022Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
4 authors at 2 institutions in 2 countries.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Microalgal proteins are promising sources for functional nutrition and a sustainable candidate for nutraceutical formulations. They also gain importance due to emerging focus on a healthy nutrition and increase in the number of chronic diseases. In this study, dried dietary species of microalga, Chlorella vulgaris, and cyanobacterium Spirulina platensis were hydrolyzed with pancreatin enzyme to obtain protein hydrolysates. The hydrolysis yield of biomass was 55.1 ± 0.1 and 64.8 ± 3.6% for C. vulgaris and S. platensis; respectively. Digestibility, as an indicator for dietary utilization, was also investigated. In vitro protein digestibility (IVPD) values depicted that cell wall structure due to the taxonomical differences affected both hydrolysis and digestibility yield of the crude biomass (p < 0.05). Epithelial cells (Vero) maintained their viability around 70%, even in relatively higher concentrations of hydrolysates in the culture. The protein hydrolysates showed no any antimicrobial activities. This study clearly shows that the conventional protein sources in nutraceutical formulations such as soy, whey, and fish proteins can be replaced by enzymatic hydrolysates of microalgae, which shows elevated digestibility values as a sustainable and reliable source.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.