Evidence map›Paper›PMID 28660419›Full record

ArticleSurgical endoscopy2018

Per oral endoscopic myotomy vs. laparoscopic Heller myotomy, does gastric extension length matter?

Mauricio Ramirez, Cecilia Zubieta, Franco Ciotola, Alfredo Amenabar, Adolfo Badaloni, Fabio Nachman, Alejandro Nieponice

Abstract read
PubMed Publisher
In one paragraph

Article in Surgical endoscopy, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 18 papers, 5 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
18citing papers in PubMed, 5 pooled it
3.1field-weighted citation impact, top 8% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

18 citing papers in PubMed, 5 syntheses or guidelines pooled it, 55 citations in OpenAlex.

  1. Pooled it
  2. Pooled it
  3. Peroral endoscopic myotomy compared to laparoscopic Heller myotomy and pneumatic dilation in the treatment of achalasia: a systematic review.Diseases of the esophagus : official journal of the International Society for Diseases of the Esophagus · 2024
    Pooled it
  4. Pooled it
  5. Pooled it
  6. Peroral endoscopic myotomyWorld journal of gastroenterology · 2022
    Trial
  7. Article
  8. Review
  9. Review
  10. Article
  11. Article
  12. Article
  13. Review
  14. Review
  15. Changes in Distensibility Index During an Incremental POEM Myotomy.Journal of gastrointestinal surgery : official journal of the Society for Surgery of the Alimentary Tract · 2022
    Article
  16. POEM, GPOEM, and ZPOEM.Digestive diseases and sciences · 2022
    Review
  17. Article
  18. Per-oral endoscopic myotomy and gastroesophageal reflux: Where do we stand after a decade of "POETRY"?Indian journal of gastroenterology : official journal of the Indian Society of Gastroenterology · 2019
    Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 1 institution in 1 country.

Mauricio RamirezEsophageal Institute, Hospital Universitario Fundacion Favaloro, Av. Beolgrano 1746, Buenos Aires, Argentina.
Cecilia ZubietaEsophageal Institute, Hospital Universitario Fundacion Favaloro, Av. Beolgrano 1746, Buenos Aires, Argentina.
Franco CiotolaEsophageal Institute, Hospital Universitario Fundacion Favaloro, Av. Beolgrano 1746, Buenos Aires, Argentina.
Alfredo AmenabarEsophageal Institute, Hospital Universitario Fundacion Favaloro, Av. Beolgrano 1746, Buenos Aires, Argentina.
Adolfo BadaloniEsophageal Institute, Hospital Universitario Fundacion Favaloro, Av. Beolgrano 1746, Buenos Aires, Argentina.
Fabio NachmanEsophageal Institute, Hospital Universitario Fundacion Favaloro, Av. Beolgrano 1746, Buenos Aires, Argentina.
Alejandro NieponiceEsophageal Institute, Hospital Universitario Fundacion Favaloro, Av. Beolgrano 1746, Buenos Aires, Argentina. nieponicea@upmc.edu.ORCID http://orcid.org/0000-0002-4126-223X
Fundacion Favaloro Hospital Universitario · AR

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

objectiveTo report our experience in POEM vs. LHM, with particular focus on myotomy extension.

backgroundPOEM has been adopted worldwide as a treatment for achalasia. While resolution of dysphagia is above 90%, postoperative reflux ranges from 10 to 57%. Myotomy length has been a controversial topic.

methodsThirty-five cases of POEM were prospectively analyzed and compared retrospectively to the last 35 patients that underwent LHM, from December 2010 to August 2016. Mean follow-up was 10 months (6/32) for POEM and 20 months (6/68) for LHM. All patients with LHM had a myotomy extension ≥3 cm on the gastric side. In POEM cases, extension was defined by direct vision (Hill type II) and never exceeded 2 cm.

resultsFollow-up was completed in 100% of patients. Efficacy (ES ≤ 3) was 33/35 (94.2%) for POEM and 32/35 (91.4%) for LHM in a short-term follow-up (p = 1.000) and 31/35 (88.6%) and 27/35 (77.1%), respectively, in a long-term follow-up (p = 1.000), with average ES drop from 9 to 1.2 (p = 0.0001) in POEM vs. 9.2 to 1.3 (p = 0.0001) in LHM. Major Postoperative complications occurred in 1 patient (leak) for LHM and 1 patient (massive capnothorax) in POEM. Hospital stay was shorter for POEM than for LHM (1.3 vs. 2.1, respectively) (p = 0.0001). Symptomatic reflux cases included 7/35 POEM (20%) vs. 6/35 LHM (17.1%) (p = 0.4620). Esophagitis signs in endoscopy appeared in 1/21 POEM (4.7%) vs. 1/22 LHM (4.5%) (p = 1.000). Patients requiring PPI included 8/35 POEM (22.8%) vs. 7/35 LHM (20%) (p = 0.6642). Further treatment (endoscopic dilation) was performed in 10/35 POEM (28.5%) vs. 8/35 LHM (22.8%).

conclusionsA shorter myotomy on the gastric side in POEM may contribute to an acceptable reflux rate with comparable relief of dysphagia. Although our follow-up for POEM is shorter than for LHM, the trends are promising and warrant future prospective studies to address this topic.

Indexed as

AphasiaEndoscopy, GastrointestinalEsophageal AchalasiaEsophagitis, PepticFemaleHeller MyotomyHumansLength of StayMaleMiddle AgedMyotomyNatural Orifice Endoscopic SurgeryPostoperative ComplicationsRetrospective StudiesTreatment OutcomeAchalasiaEndoscopic myotomyEndoscopyGastric myotomy extensionLaparoscopic heller myotomyPOEM

Identifiers

PMID28660419
OpenAlexW2729328085

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.