Evidence map›Paper›PMID 28660416›Full record

Trial reportSchmerz (Berlin, Germany)2017

[Botulinum toxin A injections in neuropathic pain : A post-hoc subgroup analysis of patients with peripheral nerve injury].

L Eitner, J Vollert, C Maier, N Attal

Abstract readMulticenter StudyRandomized Controlled Trial
PubMed Publisher
In one paragraph

Trial report in Schmerz (Berlin, Germany), 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 7 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
7citing papers in PubMed, 1 pooled it
0.7field-weighted citation impact, top 28% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

7 citing papers in PubMed, 1 synthesis or guideline pooled it, 10 citations in OpenAlex.

  1. Pooled it
  2. Review
  3. Article
  4. Article
  5. Review
  6. Review
  7. [Long-term effectiveness of topical analgesics].Schmerz (Berlin, Germany) · 2020
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors at 2 institutions in 2 countries.

L EitnerAbteilung für Schmerzmedizin, Berufsgenossenschaftliches Universitätsklinikum Bergmannsheil gGmbH, Ruhr-Universität Bochum, Bürkle de la Camp-Platz 1, 44789, Bochum, Deutschland. Lynn.Eitner@rub.de.
J VollertAbteilung für Schmerzmedizin, Berufsgenossenschaftliches Universitätsklinikum Bergmannsheil gGmbH, Ruhr-Universität Bochum, Bürkle de la Camp-Platz 1, 44789, Bochum, Deutschland.
C MaierAbteilung für Schmerzmedizin, Berufsgenossenschaftliches Universitätsklinikum Bergmannsheil gGmbH, Ruhr-Universität Bochum, Bürkle de la Camp-Platz 1, 44789, Bochum, Deutschland.
N AttalINSERM U‑987, Centre d'Evaluation et de Traitement de la Douleur, Hôpital Ambroise Paré, AP-HP, Boulogne-Billancourt, Université Versailles-Saint-Quentin, Paris, Frankreich.
BG University Hospital Bergmannsheil Bochum · DEHôpital Ambroise-Paré · FR

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

The randomized controlled trial (RCT) presented in this article showed significant relief in neuropathic pain following subcutaneous injections of botulinum toxin A over 24 weeks compared to placebo. This result was confirmed in a novel post-hoc analysis of the subgroup of 46 patients with peripheral nerve injury. Relevant adverse effects did not occur during the RCT.

Indexed as

Botulinum Toxins, Type ANeuralgiaPeripheral Nerve InjuriesDouble-Blind MethodHumansInjections, SubcutaneousNeuralgia, PostherpeticPain MeasurementPolyneuropathiesPostoperative PainQuality of LifeBotulinum Toxins, Type ABotulinum toxin APeripheral neuropathic painRisk

Identifiers

PMID28660416
OpenAlexW2725085696

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.