ArticleEuropean journal of pediatrics2017
Neonatal outcome of small for gestational age preterm infants.
Article in European journal of pediatrics, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT06919757 (Early Lung Function Trajectories), which is not on this map. Cited by 25 papers.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Early Lung Function Trajectories: Comparison Between Infants With Intrauterine Growth Restriction and Appropriately Grown Ones.
Who cites it
25 citing papers in PubMed, 58 citations in OpenAlex.
- Distinct early-life gut microbiota patterns across SGA, AGA, and LGA infants.European journal of pediatrics · 2026Article
- Changes in Fetal Hemoglobin in Very Preterm Infants Born Small for Gestational Age: A Retrospective Observational Study.Children (Basel, Switzerland) · 2026Article
- Is small for gestational age associated with reduced oxygen saturation to FiOEuropean journal of pediatrics · 2026Article
- Evaluating the efficacy of LDH and inflammatory indices in discriminating neonatal respiratory distress syndrome from transient tachypnea of the newborns.BMC pediatrics · 2025Article
- Outcome of Preterm Neonates > 32 Weeks Gestation in Relation to Three-Tiered Fetal Heart Rate Categorization.Medicina (Kaunas, Lithuania) · 2025Article
- A new birth weight chart and optimal birth weight percentiles for predicting infant mortality.Scientific reports · 2024Article
- Long-term implications of fetal growth restriction.World journal of clinical cases · 2023Review
- Severity of small-for-gestational-age and morbidity and mortality among very preterm neonates.Journal of perinatology : official journal of the California Perinatal Association · 2023Article
- The impact of small-for-gestational-age Status on the outcomes in very-Low-birth-weight (VLBW) premature infants: a prospective cohort study in Taiwan.Frontiers in pediatrics · 2023Article
- Risk factors that affect the degree of bronchopulmonary dysplasia in very preterm infants: a 5-year retrospective study.BMC pediatrics · 2022Article
- Perinatal Origins of Adult Disease and Opportunities for Health Promotion: A Narrative Review.Journal of personalized medicine · 2022Review
- Growth patterns of preterm infants in Korea.Clinical and experimental pediatrics · 2022Article
- Maternal and neonatal risk factors for neonatal respiratory distress syndrome in term neonates in Cyprus: a prospective case-control study.Italian journal of pediatrics · 2021Article
- Neurodevelopmental outcomes of singleton large for gestational age infants <29 weeks' gestation: a retrospective cohort study.Journal of perinatology : official journal of the California Perinatal Association · 2021Article
- Neonatal outcome of small for gestational age infants born at 26-33 weeks' gestation in Chinese neonatal intensive care units.Translational pediatrics · 2021Article
- Comparison of neonatal outcomes of small for gestational age and appropriate for gestational age preterm infants born at 28-36 weeks of gestation: a multicentre study in Ethiopia.BMJ paediatrics open · 2020Article
- Growth patterns during early childhood in children born small for gestational age and moderate preterm.Scientific reports · 2019Article
- Bronchopulmonary dysplasia in very preterm infants: Outcome up to preschool age, in a single center of Austria.Pediatrics international : official journal of the Japan Pediatric Society · 2019Observational
- Effect of Diarrheal Illness During Pregnancy on Adverse Birth Outcomes in Nepal.Open forum infectious diseases · 2019Article
- Perinatal Outcomes of Small for Gestational Age Neonates Born With an Isolated Single Umbilical Artery.Frontiers in pediatrics · 2019Article
Corrections and comments
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Authors and funding
3 authors at 2 institutions in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Small for gestational age (SGA) preterm neonates (birth weight < -2 SDS) are considered to have increased risk of bronchopulmonary dysplasia (BPD) compared to appropriate for GA (AGA) neonates. It is unclear if SGA infants have increased risk for respiratory distress syndrome (RDS) and mortality. We analyzed data from 515 neonates born <30 weeks GA, 98(19%) were SGA. SGA were compared to AGA by univariate analysis and logistic regression analysis (LRA). Significant variables at univariate analysis were IUGR (67 vs 7%, p = 0.000), chorioamnionitis (1 vs 13%, p = 0.017), pre-eclampsia (62 vs 18%, p = 0.000), surfactant retreatment (47 vs 25%, p = 0.000), BPD (32 vs 20%, p = 0.015), death (30 vs 12%, p = 0.000), SatO2/FiO2 on day 3 (376 vs 433, p = 0.013), and SatO2/FiO2 ratio on day 28 (400 vs 448, p = 0.000). LRA found the following associations: regarding mortality, a decreased Sat/FiO2 ratio on day 3 (OR 1.99, 95% CI 1.26-3.16, p = 0.003); regarding BPD, surfactant retreatment (3.70, 2.11-6.49, p = 0.000), being SGA (2.69, 1.36-5.36, p = 0.005), decreasing GA (1.05, 1.03-1.08, p = 0.000), decreasing SatO2/FiO2 ratio on day 3 (1.25, 1.11-1.40, p = 0.000); and regarding severe RDS, pre-eclampsia (2.68, 1.58-4.55, p = 0.000) and decreasing GA (1.06, 1.04-1.08, p = 0.000).
conclusionsIn our cohort of preterm infants, being SGA was significantly associated with BPD, but not with increased risk of mortality or RDS due to multiple pathophysiologic mechanisms. What is Known: • Small for gestational age preterm neonates are considered to have increased risk of bronchopulmonary dysplasia (BPD) compared to appropriate for GA neonates. • It is still unclear if SGA infants have increased risk for respiratory distress syndrome (RDS) and mortality. What is New: • In our cohort of 515 preterm infants (19% SGA), being SGA was significantly associated with BPD, but not with increased risk of mortality or RDS. • These results may be explained by the heterogeneity of mechanisms leading to SGA condition and by multiple mechanisms involving lung growth impairment and other factors.
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