Evidence map›Paper›PMID 28660243›Full record

ArticleeNeuro

Effects of Selective Deletion of Tyrosine Hydroxylase from Kisspeptin Cells on Puberty and Reproduction in Male and Female Mice.

Shannon B Z Stephens, Melvin L Rouse, Kristen P Tolson, Reanna B Liaw, Ruby A Parra, Navi Chahal, Alexander S Kauffman

Open access · goldAbstract read
In one paragraph

Article in eNeuro. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 28 papers.

0numbers the graph read from it
0cells of the map it votes in
28citing papers in PubMed
3.3field-weighted citation impact, top 9% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

28 citing papers in PubMed, 36 citations in OpenAlex.

  1. Article
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  4. Nutritionally Responsive PMv DAT Neurons Are Dynamically Regulated During Pubertal Transition.FASEB journal : official publication of the Federation of American Societies for Experimental Biology · 2025
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 1 institution in 1 country.

Shannon B Z StephensDepartment of Reproductive Medicine, University of California, San Diego La Jolla, CA 92093.
Melvin L RouseDepartment of Reproductive Medicine, University of California, San Diego La Jolla, CA 92093.ORCID 0000-0002-3669-2083
Kristen P TolsonDepartment of Reproductive Medicine, University of California, San Diego La Jolla, CA 92093.ORCID 0000-0002-0729-8554
Reanna B LiawDepartment of Reproductive Medicine, University of California, San Diego La Jolla, CA 92093.ORCID 0000-0002-6704-7028
Ruby A ParraDepartment of Reproductive Medicine, University of California, San Diego La Jolla, CA 92093.
Navi ChahalDepartment of Reproductive Medicine, University of California, San Diego La Jolla, CA 92093.
Alexander S KauffmanDepartment of Reproductive Medicine, University of California, San Diego La Jolla, CA 92093.ORCID 0000-0001-8631-6097
University of California System · US

Funding

UCSD/SDSU IRACDAK12GM068524 · NIGMS · UNIVERSITY OF CALIFORNIA, SAN DIEGO · PI TREJO, JOANN · 2003 to 2025
$24.4M
Testosterone-GnRH Frequency and the Evolution of PCOS in AdolescenceP50HD028934 · NICHD · UNIVERSITY OF VIRGINIA · PI HAISENLEDER, DANIEL J. · 2014 to 2018
$8.6M
The Role of FSH in Female InfertilityP50HD012303 · NICHD · UNIVERSITY OF CALIFORNIA, SAN DIEGO · PI CHANG, R JEFFREY · 1985 to 2020
$7.5M
TRAINING IN REPRODUCTIVE SCIENCEST32HD007203 · NICHD · UNIVERSITY OF CALIFORNIA, SAN DIEGO · PI PAMELA L MELLON · 1988 to 2026
$4.8M
Neuroendocrine Actions of Androgens in Female ReproductionR01HD082567 · NICHD · UNIVERSITY OF CALIFORNIA, SAN DIEGO · PI MELLON, PAMELA L · 2015 to 2019
$1.6M
Function and Molecular Phenotyping of Amygdala Kisspeptin NeuronsF32HD088060 · NICHD · UNIVERSITY OF CALIFORNIA, SAN DIEGO · PI STEPHENS, SHANNON BROOKE ZOE · 2016 to 2017
$84k
NICHD NIH HHS F32 HD088060NICHD NIH HHS P50 HD012303NICHD NIH HHS P50 HD028934NICHD NIH HHS R01 HD082567NICHD NIH HHS T32 HD007203NIGMS NIH HHS K12 GM068524
6 · The paper itself

Abstract

The neuropeptide kisspeptin, encoded by

Indexed as

AnimalsArcuate Nucleus of HypothalamusBody WeightDopamineEstradiolFemaleFertilityGonadotropinsKisspeptinsLongitudinal StudiesMaleMice, Inbred C57BLMice, TransgenicNeuronsParaventricular Hypothalamic NucleusReproductionDopamineEstradiolGonadotropinsKiss1 protein, mouseKisspeptinsTestosteroneTyrosine 3-MonooxygenasedopamineGnRHKiss1kisspeptinpubertyreproduction

Identifiers

PMID28660243
PMCPMC5480141
OpenAlexW2626314076

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.