Evidence map›Paper›PMID 28660242›Full record

ReviewCellular and molecular gastroenterology and hepatology2017

Bacterial Autophagy: Offense and Defense at the Host-Pathogen Interface.

James E Casanova

Open access · goldAbstract readReview
In one paragraph

Review in Cellular and molecular gastroenterology and hepatology, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 43 papers.

0numbers the graph read from it
0cells of the map it votes in
43citing papers in PubMed
5.0field-weighted citation impact, top 4% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

43 citing papers in PubMed, 57 citations in OpenAlex.

  1. Article
  2. Article
  3. Restricting intracellularAutophagy · 2026
    Article
  4. Biomedicines · 2025
    Review
  5. Article
  6. Article
  7. Article
  8. Molecular biology of the cell · 2025
    Article
  9. Article
  10. Review
  11. Staphylococcal mastitis in dairy cows.Frontiers in veterinary science · 2024
    Review
  12. Article
  13. Article
  14. Review
  15. Article
  16. Article
  17. Autophagy and Skin Diseases.Frontiers in pharmacology · 2022
    Review
  18. Interaction Between Autophagy andFrontiers in cellular and infection microbiology · 2022
    Review
  19. Review
  20. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

1 author at 1 institution in 1 country.

James E CasanovaDepartment of Cell Biology, Department of Microbiology, Immunology and Cancer Biology, University of Virginia Health System, Charlottesville, Virginia.
University of Virginia Health System · US

Funding

MECHANISMS OF SALMONELLA INVASION AND TRANSMIGRATIONR01DK058536 · NIDDK · UNIVERSITY OF VIRGINIA CHARLOTTESVILLE · PI CASANOVA, JAMES E. · 2000 to 2013
$3.6M
NIDDK NIH HHS R01 DK058536
6 · The paper itself

Abstract

Autophagy is a fundamental cellular process used for the turnover and recycling of cytosolic components and damaged organelles. Originally characterized as a response to cellular stress, it now is well established that autophagy also is used as a defensive mechanism to combat the infection of host cells by intracellular pathogens. However, although this defensive strategy does limit the proliferation of most pathogens within their host cells, successful pathogens have evolved countermeasures that subvert or circumvent the autophagic response. In this review, we discuss the mechanisms used by a number of these pathogens to escape autophagy, with a particular focus on

Indexed as

AktAutophagyDAG, diacylglycerolFAKFAK, focal adhesion kinaseIFN, interferonInterferonLC3, microtubule-associated light chain 3mTORC1, mechanistic target of rapamycin 1SalmonellaSCV, Salmonella-containing vacuoleT3SS, type III secretion systemTLR, Toll-like receptorXenophagy

Identifiers

PMID28660242
PMCPMC5480303
OpenAlexW2610776233

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.