Evidence map›Paper›PMID 28660172›Full record

ArticleFrontiers in oncology2017

Pineal Region Glioblastoma, a Case Report and Literature Review.

Hayley Beacher Stowe, C Ryan Miller, Jing Wu, Dina M Randazzo, Andrew Wenhua Ju

Open access · goldAbstract readCase Reports
In one paragraph

Article in Frontiers in oncology, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 7 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
7citing papers in PubMed, 1 pooled it
1.7field-weighted citation impact, top 16% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

7 citing papers in PubMed, 1 synthesis or guideline pooled it, 25 citations in OpenAlex.

  1. Pooled it
  2. Article
  3. Review
  4. Article
  5. Article
  6. Article
  7. Childhood Pineal Glioblastoma: Case Report.Journal of pediatric neurosciences
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors at 4 institutions in 1 country.

Hayley Beacher StoweDepartment of Radiation Oncology, Brody School of Medicine, Greenville, NC, United States.
C Ryan MillerDepartment of Pathology, University of North Carolina School of Medicine, Chapel Hill, NC, United States.
Jing WuCenter for Cancer Research National Cancer Institute, Bethesda, MD, United States.
Dina M RandazzoDepartment of Neuro-Oncology, Duke Health, Durham, NC, United States.
Andrew Wenhua JuDepartment of Radiation Oncology, Brody School of Medicine, Greenville, NC, United States.
East Carolina University · USDuke University Health System · USNational Cancer Institute · USUniversity of North Carolina at Chapel Hill · US

Funding

Brain Tumor Clinical and Clinical Research Program (Clinical Support Services)ZIDBC011642 · NCI · DIVISION OF BASIC SCIENCES - NCI · PI OZER, BYRAM · 2015 to 2025
$23.4M
6 · The paper itself

Abstract

introductionPineal region glioblastoma multiforme (GBM) is a rare disease entity with a generally poor prognosis. We present a case of a patient with an unresectable pineal region GBM treated with chemoradiation with favorable outcome. CASE

backgroundA 65-year-old patient who was presented with visual symptoms was found to have a pineal region tumor on imaging. A stereotactic biopsy showed a World Health Organization Grade IV GBM, DISCUSSION: On our review of the literature, 24 cases of pineal region GBM have been reported. The median reported survival for these previously reported cases was 6 months (range, 2-24 months). This patient has the longest overall survival reported to date for a patient with this diagnosis. This is the first patient in the literature with pineal region GBM who has been reported to have MGMT promoter methylation. CONCLUDING REMARKS: Although pineal region GBM is a rare disease entity with a generally poor prognosis, long-term survival is achievable for select patients. MGMT promoter methylation may potentially have prognostic value. Favorable control of recurrent disease with the use of bevacizumab is possible.

Indexed as

bevacizumabglioblastomaO-6-methylguanine-DNA methyltransferasepinealradiotherapytemozolomide

Identifiers

PMID28660172
PMCPMC5466962
OpenAlexW2624182525

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.