Evidence map›Paper›PMID 28660088›Full record

ArticleInternational journal of inflammation2017

High Vitamin D Levels May Downregulate Inflammation in Patients with Behçet's Disease.

Fahd Adeeb, Maria Usman Khan, Xia Li, Austin G Stack, Joseph Devlin, Alexander D Fraser

Registry-linked trialOpen access · goldAbstract read
In one paragraph

Article in International journal of inflammation, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT04308161 (The Effectiveness of Topical Oral Vitamin D Gel in Prevention of Radiation-induced Oral Mucositis), which is not on this map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
1.2field-weighted citation impact, top 22% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT04308161 phase2unknown statusnot on this mapstarted 2019, after this paper: background citation

The Effectiveness of Topical Oral Vitamin D Gel in Prevention of Radiation-induced Oral Mucositis

TypeinterventionalSponsorHams Hamed AbdelrahmanRan2019 to 2020Enrolled45ConditionsOral Mucositis Due to RadiationArmsvitamin D oral gel, Miconazole Topical Gel, BBC oral spray, Oracure gel, Alkamisr sachets
3 · Its place in the literature

Who cites it

2 citing papers in PubMed, 13 citations in OpenAlex.

  1. Article
  2. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 3 institutions in 3 countries.

Fahd AdeebDepartment of Rheumatology, University Hospital Limerick, Limerick, Ireland.ORCID 0000-0002-9444-0810
Maria Usman KhanDepartment of Rheumatology, University Hospital Limerick, Limerick, Ireland.
Xia LiGraduate Entry Medical School, University of Limerick, Limerick, Ireland.
Austin G StackGraduate Entry Medical School, University of Limerick, Limerick, Ireland.
Joseph DevlinDepartment of Rheumatology, University Hospital Limerick, Limerick, Ireland.
Alexander D FraserDepartment of Rheumatology, University Hospital Limerick, Limerick, Ireland.
University of Limerick · IELa Trobe University · AUUniversity Hospital Limerick · IE

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Vitamin D plays a significant role in the immune system modulation and may confer a protective role in autoimmune diseases. We conducted a case-control study to compare 25(OH)D levels in patients with BD who were managed at a regional rheumatology programme in the midwest region of Ireland compared to matched controls. Healthy controls were selected from the Irish health system and matched in 1 : 5 ratio for age, sex, and the month of the year. 25(OH)D levels <20 nmol/L were classified as deficient while levels between 20 and 40 nmol/L were classified as insufficient. Differences between groups were assessed using Mann-Whitney test and associations between cases and controls were expressed as odds ratios and 95% confidence intervals. Nineteen patients with BD were compared with 95 controls matched by age, sex, and month of blood draw. 25(OH)D levels were significantly higher in patients in BD than in matched controls (median values: 45 nmol/L versus 22 nmol/L,

Identifiers

PMID28660088
PMCPMC5474237
OpenAlexW2620852095

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.