Evidence map›Paper›PMID 28659913›Full record

ArticleFrontiers in immunology2017

Guillermo E Marcial, Amanda L Ford, Michael J Haller, Salvador A Gezan, Natalie A Harrison, Dan Cai, Julie L Meyer, Daniel J Perry, Mark A Atkinson, Clive H Wasserfall and 5 more

Registry-linked trialOpen access · goldAbstract read
In one paragraph

Article in Frontiers in immunology, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT02349360 (Safety, Tolerability and Host Response to Lactobacillus Johnsonii), which is not on this map. Cited by 59 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
59citing papers in PubMed, 1 pooled it
2.6field-weighted citation impact, top 10% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT02349360 phase1 / phase2completednot on this map

Safety, Tolerability and Host Response to Lactobacillus Johnsonii

TypeinterventionalSponsorUniversity of FloridaRan2015 to 2016Enrolled42ConditionsHealthyArmsL. johnsonii N6.2, Placebo
3 · Its place in the literature

Who cites it

59 citing papers in PubMed, 1 synthesis or guideline pooled it, 99 citations in OpenAlex.

  1. Pooled it
  2. Trial
  3. Adjuvant Probiotics ofFrontiers in endocrinology · 2022
    Trial
  4. Article
  5. Journal of agricultural and food chemistry · 2026
    Article
  6. Review
  7. Foods (Basel, Switzerland) · 2026
    Article
  8. Review
  9. Review
  10. Gut microbes · 2025
    Article
  11. Review
  12. Review
  13. Article
  14. Metabolites · 2025
    Article
  15. Article
  16. Review
  17. Targeting Lactobacillus johnsonii to reverse chronic kidney disease.Signal transduction and targeted therapy · 2024
    Article
  18. Tryptophan metabolism and piglet diarrhea: Where we stand and the challenges ahead.Animal nutrition (Zhongguo xu mu shou yi xue hui) · 2024
    Article
  19. Erucic acid utilization byFrontiers in microbiology · 2024
    Article
  20. Gut microbes · 2023
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

15 authors at 1 institution in 1 country.

Guillermo E MarcialDepartment of Microbiology and Cell Science, Genetics Institute, Institute of Food and Agricultural Sciences, University of Florida, Gainesville, FL, United States.
Amanda L FordFood Science and Human Nutrition Department, Institute of Food and Agricultural Sciences, University of Florida, Gainesville, FL, United States.
Michael J HallerDepartment of Pediatrics, College of Medicine, University of Florida, Gainesville, FL, United States.
Salvador A GezanSchool of Forest Resources and Conservation, Institute of Food and Agricultural Sciences, University of Florida, Gainesville, FL, United States.
Natalie A HarrisonDepartment of Microbiology and Cell Science, Genetics Institute, Institute of Food and Agricultural Sciences, University of Florida, Gainesville, FL, United States.
Dan CaiDepartment of Microbiology and Cell Science, Genetics Institute, Institute of Food and Agricultural Sciences, University of Florida, Gainesville, FL, United States.
Julie L MeyerDepartment of Soil and Water Science, Institute of Food and Agricultural Sciences, University of Florida, Gainesville, FL, United States.
Daniel J PerryDepartment of Pathology, Immunology, and Laboratory Medicine, College of Medicine, University of Florida, Gainesville, FL, United States.
Mark A AtkinsonDepartment of Pathology, Immunology, and Laboratory Medicine, College of Medicine, University of Florida, Gainesville, FL, United States.
Clive H WasserfallDepartment of Pathology, Immunology, and Laboratory Medicine, College of Medicine, University of Florida, Gainesville, FL, United States.
Timothy GarrettDepartment of Pathology, Immunology, and Laboratory Medicine, College of Medicine, University of Florida, Gainesville, FL, United States.
Claudio F GonzalezDepartment of Microbiology and Cell Science, Genetics Institute, Institute of Food and Agricultural Sciences, University of Florida, Gainesville, FL, United States.
Todd M BruskoDepartment of Pathology, Immunology, and Laboratory Medicine, College of Medicine, University of Florida, Gainesville, FL, United States.
Wendy J DahlFood Science and Human Nutrition Department, Institute of Food and Agricultural Sciences, University of Florida, Gainesville, FL, United States.
Graciela L LorcaDepartment of Microbiology and Cell Science, Genetics Institute, Institute of Food and Agricultural Sciences, University of Florida, Gainesville, FL, United States.
University of Florida · US

Funding

Project 3P01AI042288 · NIAID · UNIVERSITY OF FLORIDA · PI Todd Michael Brusko · 1997 to 2026
$32.9M
The CD226 costimulatory axis in type 1 diabetesR01DK106191 · NIDDK · UNIVERSITY OF FLORIDA · PI Todd Michael Brusko · 2016 to 2026
$4.4M
NIAID NIH HHS P01 AI042288NIDDK NIH HHS R01 DK106191
6 · The paper itself

Abstract

trial registrationThis trial was registered at http://clinicaltrials.gov as NCT02349360.

Indexed as

diabetes type Igastrointestinal symptomimmunological responseindoleamine-2,3-dioxygenaseLactobacillus johnsoniimicrobiomeprobioticT cell

Identifiers

PMID28659913
PMCPMC5466969
OpenAlexW2622633708

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.