ArticleFrontiers in neurology2017
Pre-Stroke Modified Rankin Scale: Evaluation of Validity, Prognostic Accuracy, and Association with Treatment.
Article in Frontiers in neurology, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 57 papers, 7 of them syntheses that pooled it.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
57 citing papers in PubMed, 7 syntheses or guidelines pooled it.
- Reperfusion therapies for ischemic stroke in dementia and cognitive impairment: A systematic review and meta-analysis.International journal of stroke : official journal of the International Stroke Society · 2024Pooled it
- Intravenous thrombolysis in acute ischemic stroke patients with pre-stroke disability: A systematic review and meta-analysis.Brain and behavior · 2024Pooled it
- Role of frailty in predicting outcomes after stroke: a systematic review and meta-analysis.Frontiers in psychiatry · 2024Pooled it
- Prevalence and implications of frailty in acute stroke: systematic review & meta-analysis.Age and ageing · 2022Pooled it
- Outcome Prediction Models for Endovascular Treatment of Ischemic Stroke: Systematic Review and External Validation.Stroke · 2022Pooled it
- Endovascular thrombectomy in acute ischemic stroke patients with prestroke disability (mRS ≥2): A systematic review and meta-analysis.Frontiers in neurology · 2022Pooled it
- Pooled it
- Brain Frailty and Functional Outcomes After Thrombolysis for Acute Ischemic Stroke.JAMA network open · 2025Trial
- Unsupervised robot-assisted rehabilitation after stroke: feasibility, effect on therapy dose, and user experience.Journal of neuroengineering and rehabilitation · 2024Trial
- Repeated Measures of Modified Rankin Scale Scores to Assess Functional Recovery From Stroke: AFFINITY Study Findings.Journal of the American Heart Association · 2022Trial
- Response to "Perhaps Fewer, but Faster: Should we Rethink the 90% Stroke Unit Admission Standard?"European stroke journal · 2026Article
- Initial Phase Angle Is Independently Associated With Functional Independence at 6 Months After Stroke.Geriatrics & gerontology international · 2026Observational
- Endovascular therapy in acute ischaemic stroke patients with prestroke dependency-an EVA-TRISP cohort study.European stroke journal · 2026Observational
- Article
- Deep grey nuclei automated assessment in acute-subacute phase of middle cerebral artery cortical stroke helps predict the 3-month outcome.Brain imaging and behavior · 2026Article
- Cumulative Incidence of Stroke Disability and Mortality Following Emergency Department Discharge for Dizziness: A Cohort Study.Annals of emergency medicine · 2026Article
- Comparative effectiveness of Tenecteplase and Alteplase for ischemic stroke: real-world data from a stroke center.BMC neurology · 2026Article
- Interictal epileptiform activity in the acute stroke phase: an independent predictor of poor outcome.European stroke journal · 2026Article
- Pre-stroke Functional Status in Patients Undergoing Mechanical Thrombectomy: How Relevant Are False Estimations in the Emergency Setting?Clinical neuroradiology · 2025Article
- The Relationship Between Brain Frailty and Physical Function in Patients With Stroke Undergoing Rehabilitation.Cureus · 2025Article
Corrections and comments
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Authors and funding
11 authors.
Funding
Abstract
background and purposeThe modified Rankin Scale (mRS) was designed to measure poststroke recovery but is often used to describe pre-stroke disability. We sought to evaluate three aspects of pre-stroke mRS: validity as a measure of pre-stroke disability; prognostic accuracy and association of pre-stroke mRS scores, and process of care.
methodsWe used data from a large, UK clinical registry. For analysis of validity, we compared pre-stroke mRS against other markers of pre-stroke function (age, comorbidity index, care needs). For analysis of prognostic accuracy, we described univariable and multivariable models comparing pre-stroke mRS and other prognostic variables against a variety of outcomes (early and late mortality, length of stay, institutionalization, incident complications). Finally, we described association of pre-stroke mRS and components of evidence-based stroke care (early neuroimaging, admission to stroke unit, assessment of swallow).
resultsWe analyzed data of 2,491 stroke patients. Concurrent validity analyses suggested statistically significant, but modest correlations between pre-stroke mRS and chosen variables (rho >0.40;
conclusionResults suggest that pre-stroke mRS has some concurrent validity and is a robust predictor of prognosis. This association is not explained by the influence of pre-stroke mRS on care pathways.
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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.