Evidence map›Paper›PMID 28659817›Full record

ArticleFrontiers in physiology2017

Cobalt Chloride Upregulates Impaired HIF-1α Expression to Restore Sevoflurane Post-conditioning-Dependent Myocardial Protection in Diabetic Rats.

Jianjiang Wu, Long Yang, Peng Xie, Jin Yu, Tian Yu, Haiying Wang, Yiliyaer Maimaitili, Jiang Wang, Haiping Ma, Yining Yang and 1 more

Open access · goldAbstract read
In one paragraph

Article in Frontiers in physiology, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 7 papers.

0numbers the graph read from it
0cells of the map it votes in
7citing papers in PubMed
1.3field-weighted citation impact, top 21% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

7 citing papers in PubMed, 17 citations in OpenAlex.

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4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

11 authors at 3 institutions in 1 country.

Jianjiang WuDepartment of Anesthesiology, The First Affiliated Hospital of Xinjiang Medical UniversityUrumqi, China.
Long YangDepartment of Anesthesiology, The First Affiliated Hospital of Xinjiang Medical UniversityUrumqi, China.
Peng XieDepartment of Anesthesiology, The First Affiliated Hospital of Xinjiang Medical UniversityUrumqi, China.
Jin YuDepartment of Anesthesiology, The First Affiliated Hospital of Xinjiang Medical UniversityUrumqi, China.
Tian YuDepartment of Anesthesiology and Guizhou Key Laboratory of Anesthesia and Organ Protection, Zunyi Medical CollegeZunyi, China.
Haiying WangDepartment of Anesthesiology and Guizhou Key Laboratory of Anesthesia and Organ Protection, Zunyi Medical CollegeZunyi, China.
Yiliyaer MaimaitiliDepartment of Anesthesiology, The First Affiliated Hospital of Xinjiang Medical UniversityUrumqi, China.
Jiang WangDepartment of Anesthesiology, The First Affiliated Hospital of Xinjiang Medical UniversityUrumqi, China.
Haiping MaDepartment of Anesthesiology, The First Affiliated Hospital of Xinjiang Medical UniversityUrumqi, China.
Yining YangDepartment of Cardiology, The First Affiliated Hospital of Xinjiang Medical UniversityUrumqi, China.
Hong ZhengDepartment of Anesthesiology, The First Affiliated Hospital of Xinjiang Medical UniversityUrumqi, China.
First Affiliated Hospital of Xinjiang Medical University · CNXinjiang Medical University · CNZunyi Medical University · CN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Previous studies from our group have demonstrated that sevoflurane post-conditioning (SPC) protects against myocardial ischemia reperfusion injury via elevating the intranuclear expression of hypoxia inducible factor-1 alpha (HIF-1α). However, diabetic SPC is associated with decreased myocardial protection and disruption of the HIF-1 signaling pathway. Previous studies have demonstrated that cobalt chloride (CoCl

Indexed as

diabetic statehypoxia inducible factor-1ischemia-reperfusionmyocardial protectionsevoflurane post-conditioning

Identifiers

PMID28659817
PMCPMC5468378
OpenAlexW2625845242

What OpenQuestion holds

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LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.