Evidence map›Paper›PMID 28659627›Full record

ArticleScientific reports2017

Anti-parasite therapy drives changes in human visceral leishmaniasis-associated inflammatory balance.

Théo Araújo-Santos, Bruno B Andrade, Leonardo Gil-Santana, Nívea F Luz, Priscila L Dos Santos, Fabrícia A de Oliveira, Meirielly Lima Almeida, Roseane Nunes de Santana Campos, Patrícia T Bozza, Roque P Almeida and 1 more

Open access · goldAbstract read
In one paragraph

Article in Scientific reports, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 27 papers.

0numbers the graph read from it
0cells of the map it votes in
27citing papers in PubMed
5.0field-weighted citation impact, top 5% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

27 citing papers in PubMed, 41 citations in OpenAlex.

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  10. The intersection of hostMicrobiology and molecular biology reviews : MMBR · 2024
    Review
  11. Elucidating the role played by bone marrow in visceral leishmaniasis.Frontiers in cellular and infection microbiology · 2023
    Review
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

11 authors at 5 institutions in 1 country.

Théo Araújo-SantosInstituto Gonçalo Moniz, Fundação Oswaldo Cruz, 40296-710, Salvador, Brazil.ORCID 0000-0001-9861-6660
Bruno B AndradeInstituto Gonçalo Moniz, Fundação Oswaldo Cruz, 40296-710, Salvador, Brazil.
Leonardo Gil-SantanaInstituto Gonçalo Moniz, Fundação Oswaldo Cruz, 40296-710, Salvador, Brazil.
Nívea F LuzInstituto Gonçalo Moniz, Fundação Oswaldo Cruz, 40296-710, Salvador, Brazil.
Priscila L Dos SantosDepartamento de Medicina e Patologia, Hospital Universitário, Universidade Federal de Sergipe, 49060-100, Aracaju, Sergipe, Brazil.
Fabrícia A de OliveiraDepartamento de Medicina e Patologia, Hospital Universitário, Universidade Federal de Sergipe, 49060-100, Aracaju, Sergipe, Brazil.
Meirielly Lima AlmeidaDepartamento de Medicina e Patologia, Hospital Universitário, Universidade Federal de Sergipe, 49060-100, Aracaju, Sergipe, Brazil.
Roseane Nunes de Santana CamposDepartamento de Medicina e Patologia, Hospital Universitário, Universidade Federal de Sergipe, 49060-100, Aracaju, Sergipe, Brazil.
Patrícia T BozzaInstituto Oswaldo Cruz, Fundação Oswaldo Cruz, 21045-900, Rio de Janeiro, Rio de Janeiro, Brazil.
Roque P AlmeidaDepartamento de Medicina e Patologia, Hospital Universitário, Universidade Federal de Sergipe, 49060-100, Aracaju, Sergipe, Brazil. roquepachecoalmeida@gmail.com.
Valeria M BorgesInstituto Gonçalo Moniz, Fundação Oswaldo Cruz, 40296-710, Salvador, Brazil. vborges@bahia.fiocruz.br.ORCID 0000-0002-2775-5409
Universidade Federal de Sergipe · BRFundação de Amparo à Pesquisa do Estado da Bahia · BRFundação Oswaldo Cruz · BRUniversidade Federal da Bahia · BRUniversidade Federal do Oeste da Bahia · BR

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Visceral leishmaniasis (VL) remains a major public health problem worldwide. Cytokine balance is thought to play a critical role in the development of this disease. Here, we perform a prospective exploratory study addressing whether simultaneous assessment of circulating levels of different lipid mediators and cytokines could highlight specific pathways involved with VL pathogenesis. VL patients displayed substantial increases in serum levels of Prostaglandin F

Indexed as

Leishmania donovaniAdolescentAntiprotozoal AgentsBiomarkersChildCytokinesEnzyme-Linked Immunosorbent AssayFemaleHumansInflammation MediatorsLeishmaniasis, VisceralMaleYoung AdultAntiprotozoal AgentsBiomarkersCytokinesInflammation Mediators

Identifiers

PMID28659627
PMCPMC5489532
OpenAlexW2685131096

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.