Evidence map›Paper›PMID 28659620›Full record

ArticleScientific reports2017

Combined influence of poor health behaviours on the prevalence and 15-year incidence of age-related macular degeneration.

Bamini Gopinath, Gerald Liew, Victoria M Flood, Nichole Joachim, George Burlutsky, Paul Mitchell

Open access · goldAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Scientific reports, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 6 papers, 2 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
6citing papers in PubMed, 2 pooled it
1.9field-weighted citation impact, top 15% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

6 citing papers in PubMed, 2 syntheses or guidelines pooled it, 12 citations in OpenAlex.

  1. Pooled it
  2. Pooled it
  3. Article
  4. Genetic Susceptibility, Diet Quality, and Two-Step Progression in Drusen Size.Investigative ophthalmology & visual science · 2020
    Article
  5. The flicker response of venous oxygen saturation is significantly reduced in the early and late stages of age-related macular degeneration.Graefe's archive for clinical and experimental ophthalmology = Albrecht von Graefes Archiv fur klinische und experimentelle Ophthalmologie · 2020
    Article
  6. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 3 institutions in 1 country.

Bamini GopinathCentre for Vision Research, Westmead Institute for Medical Research, University of Sydney, Sydney, NSW, Australia. bamini.gopinath@sydney.edu.au.
Gerald LiewCentre for Vision Research, Westmead Institute for Medical Research, University of Sydney, Sydney, NSW, Australia.
Victoria M FloodFaculty of Health Sciences, University of Sydney, Sydney, NSW, Australia.
Nichole JoachimCentre for Vision Research, Westmead Institute for Medical Research, University of Sydney, Sydney, NSW, Australia.
George BurlutskyCentre for Vision Research, Westmead Institute for Medical Research, University of Sydney, Sydney, NSW, Australia.
Paul MitchellCentre for Vision Research, Westmead Institute for Medical Research, University of Sydney, Sydney, NSW, Australia.
Westmead Institute for Medical Research · AUThe University of Sydney · AUWestmead Hospital · AU

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

We aimed to establish the collective influence of four lifestyle practices (physical activity, diet, smoking and alcohol consumption) on the prevalence and incidence of AMD. At baseline, 2428 participants aged 49+ with complete lifestyle and AMD data were examined, and of these, 1903 participants were re-examined 15 years later. AMD was assessed from retinal photographs. A health behaviour score was calculated, allocating 1 point for each poor behaviour: current smoking; fruits and vegetables consumed <4 serves daily; <3 episodes of physical activity per week; and >2 alcoholic drinks per day. Cross-sectional analysis showed that participants who engaged in all 4 poor health behaviours (n = 29) versus those who did not engage in unhealthy behaviours (reference group; n = 677) had greater odds of any and late AMD: multivariable-adjusted OR, 5.14 (95% CI, 1.04-25.45) and OR 29.53 (95% CI 2.72-321.16), respectively. A marginally non-significant association was observed between increasing number of poor health behaviours and 15-year incidence of early AMD (multivariable-adjusted P-trend = 0.08). Our data suggests that motivating patients with AMD to eat better, exercise more, limit alcohol intake and avoid smoking seems advisable to decelerate the development or worsening of existing AMD.

Indexed as

Health Risk BehaviorsAgedAlcohol DrinkingCross-Sectional StudiesFemaleHumansIncidenceLife StyleMacular DegenerationMaleMiddle AgedPrevalencePublic Health SurveillanceRisk AssessmentRisk FactorsSmoking

Identifiers

PMID28659620
PMCPMC5489492
OpenAlexW2634949457

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.