Evidence map›Paper›PMID 28659506›Full record

ReviewEuropean respiratory review : an official journal of the European Respiratory Society2017

Cell therapy for lung disease.

Sabine Geiger, Daniela Hirsch, Felix G Hermann

Registry-linked trialOpen access · diamondAbstract readReview
In one paragraph

Review in European respiratory review : an official journal of the European Respiratory Society, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT04487691 (Autologous Nebulized Platelet Lysate for Post COVID-19 Syndrome), which is not on this map. Cited by 50 papers.

0numbers the graph read from it
0cells of the map it votes in
50citing papers in PubMed
6.6field-weighted citation impact, top 3% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT04487691 naterminatednot on this mapstarted 2020, after this paper: background citation

Autologous Nebulized Platelet Lysate for Post COVID-19 Syndrome

TypeinterventionalSponsorRegenexx, LLCRan2020 to 2021Enrolled1ConditionsCovid19ArmsNebulized Platelet Lysate, Nebulized Sterile Saline
3 · Its place in the literature

Who cites it

50 citing papers in PubMed, 87 citations in OpenAlex.

  1. Trial
  2. Pulmonary fibrosis: Emerging targets and novel therapeutics.The Journal of international medical research · 2026
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors at 1 institution in 1 country.

Sabine GeigerPreclinical Development, Apceth Biopharma GmbH, Munich, Germany f.hermann@apceth.com.
Daniela HirschPreclinical Development, Apceth Biopharma GmbH, Munich, Germany.
Felix G HermannPreclinical Development, Apceth Biopharma GmbH, Munich, Germany.
Apceth Biopharma (Germany) · DE

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Besides cancer and cardiovascular diseases, lung disorders are a leading cause of morbidity and death worldwide. For many disease conditions no effective and curative treatment options are available. Cell therapies offer a novel therapeutic approach due to their inherent anti-inflammatory and anti-fibrotic properties. Mesenchymal stem/stromal cells (MSC) are the most studied cell product. Numerous preclinical studies demonstrate an improvement of disease-associated parameters after MSC administration in several lung disorders, including chronic obstructive pulmonary disease, acute respiratory distress syndrome and idiopathic pulmonary fibrosis. Furthermore, results from clinical studies using MSCs for the treatment of various lung diseases indicate that MSC treatment in these patients is safe. In this review we summarise the results of preclinical and clinical studies that indicate that MSCs are a promising therapeutic approach for the treatment of lung diseases. Nevertheless, further investigations are required.

Indexed as

Mesenchymal Stem Cell TransplantationAnimalsCell DifferentiationCell ProliferationHumansLungLung DiseasesRecovery of FunctionRegenerationTreatment Outcome

Identifiers

PMID28659506
PMCPMC9489130
OpenAlexW2731374312

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC
Read underepoch 390

Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.