Evidence map›Paper›PMID 28659491›Full record

ReviewMicrobiology and molecular biology reviews : MMBR2017

Physiological and Molecular Understanding of Bacterial Polysaccharide Monooxygenases.

Marco Agostoni, John A Hangasky, Michael A Marletta

Abstract readReview
In one paragraph

Review in Microbiology and molecular biology reviews : MMBR, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 19 papers.

0numbers the graph read from it
0cells of the map it votes in
19citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

19 citing papers in PubMed.

  1. Article
  2. Immunization with lytic polysaccharide monooxygenase CbpD induces protective immunity againstProceedings of the National Academy of Sciences of the United States of America · 2023
    Article
  3. Characterization of a unique polysaccharide monooxygenase from the plant pathogenProceedings of the National Academy of Sciences of the United States of America · 2023
    Article
  4. Review
  5. Article
  6. Review
  7. Article
  8. Article
  9. Article
  10. Article
  11. Review
  12. Article
  13. Article
  14. Article
  15. Article
  16. Molecular mechanism of the chitinolytic peroxygenase reaction.Proceedings of the National Academy of Sciences of the United States of America · 2020
    Article
  17. Article
  18. Review
  19. Reactivity of OProceedings of the National Academy of Sciences of the United States of America · 2018
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors.

Marco AgostoniCalifornia Institute for Quantitative Biosciences (QB3), University of California, Berkeley, Berkeley, California, USA.
John A HangaskyCalifornia Institute for Quantitative Biosciences (QB3), University of California, Berkeley, Berkeley, California, USA.
Michael A MarlettaCalifornia Institute for Quantitative Biosciences (QB3), University of California, Berkeley, Berkeley, California, USA marletta@berkeley.edu.ORCID 0000-0001-8715-4253

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Bacteria have long been known to secrete enzymes that degrade cellulose and chitin. The degradation of these two polymers predominantly involves two enzyme families that work synergistically with one another: glycoside hydrolases (GHs) and polysaccharide monooxygenases (PMOs). Although bacterial PMOs are a relatively recent addition to the known biopolymer degradation machinery, there is an extensive amount of literature implicating PMO in numerous physiological roles. This review focuses on these diverse and physiological aspects of bacterial PMOs, including facilitating endosymbiosis, conferring a nutritional advantage, and enhancing virulence in pathogenic organisms. We also discuss the correlation between the presence of PMOs and bacterial lifestyle and speculate on the advantages conferred by PMOs under these conditions. In addition, the molecular aspects of bacterial PMOs, as well as the mechanisms regulating PMO expression and the function of additional domains associated with PMOs, are described. We anticipate that increasing research efforts in this field will continue to expand our understanding of the molecular and physiological roles of bacterial PMOs.

Indexed as

AnimalsBacteriaBacterial InfectionsCelluloseChitinGlycoside HydrolasesHost-Pathogen InteractionsHumansListeria monocytogenesMixed Function OxygenasesPolysaccharides, BacterialPseudomonasSubstrate SpecificityVirulence FactorsCelluloseChitinGlycoside HydrolasesMixed Function OxygenasesPolysaccharides, BacterialVirulence Factorscellulolytic enzymescellulosechitinendosymbiontsinfectious diseaseListeria monocytogenesmonooxygenasespolysaccharidesPseudomonas

Identifiers

PMID28659491
PMCPMC5584313

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.