Evidence map›Paper›PMID 28659490›Full record

ArticleMolecular & cellular proteomics : MCP2017

RhoA Inhibitor Treatment At Acute Phase of Spinal Cord Injury May Induce Neurite Outgrowth and Synaptogenesis.

Stephanie Devaux, Dasa Cizkova, Khalil Mallah, Melodie Anne Karnoub, Zahra Laouby, Firas Kobeissy, Juraj Blasko, Serge Nataf, Laurent Pays, Céline Mériaux and 2 more

Open access · hybridAbstract read
In one paragraph

Article in Molecular & cellular proteomics : MCP, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 18 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
18citing papers in PubMed, 1 pooled it
1.8field-weighted citation impact, top 16% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

18 citing papers in PubMed, 1 synthesis or guideline pooled it, 59 citations in OpenAlex.

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  13. Immortalized Dorsal Root Ganglion Neuron Cell Lines.Frontiers in cellular neuroscience · 2020
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

12 authors at 5 institutions in 3 countries.

Stephanie DevauxFrom the ‡Univ. Lille, Inserm, U-1192 - Laboratoire Protéomique, Réponse Inflammatoire et Spectrométrie de Masse-PRISM, F-59000 Lille, France.
Dasa CizkovaFrom the ‡Univ. Lille, Inserm, U-1192 - Laboratoire Protéomique, Réponse Inflammatoire et Spectrométrie de Masse-PRISM, F-59000 Lille, France.
Khalil MallahFrom the ‡Univ. Lille, Inserm, U-1192 - Laboratoire Protéomique, Réponse Inflammatoire et Spectrométrie de Masse-PRISM, F-59000 Lille, France.
Melodie Anne KarnoubFrom the ‡Univ. Lille, Inserm, U-1192 - Laboratoire Protéomique, Réponse Inflammatoire et Spectrométrie de Masse-PRISM, F-59000 Lille, France.
Zahra LaoubyFrom the ‡Univ. Lille, Inserm, U-1192 - Laboratoire Protéomique, Réponse Inflammatoire et Spectrométrie de Masse-PRISM, F-59000 Lille, France.
Firas Kobeissy‖Department of Biochemistry and Molecular Genetics, Faculty of Medicine, American University of Beirut.
Juraj Blasko**Institute of Neurobiology, Slovak Academy of Sciences, Soltesovej 4-6 Kosice, Slovakia.
Serge Nataf‡‡Univ Lyon, CarMeN laboratory, Inserm U1060, INRA U1397, Université Claude Bernard Lyon 1, INSA Lyon, Charles Merieux Medical School, Fr-69600, Oullins, France.
Laurent Pays‡‡Univ Lyon, CarMeN laboratory, Inserm U1060, INRA U1397, Université Claude Bernard Lyon 1, INSA Lyon, Charles Merieux Medical School, Fr-69600, Oullins, France.
Céline MériauxFrom the ‡Univ. Lille, Inserm, U-1192 - Laboratoire Protéomique, Réponse Inflammatoire et Spectrométrie de Masse-PRISM, F-59000 Lille, France.ORCID 0000-0002-2413-2599
Isabelle FournierFrom the ‡Univ. Lille, Inserm, U-1192 - Laboratoire Protéomique, Réponse Inflammatoire et Spectrométrie de Masse-PRISM, F-59000 Lille, France.ORCID 0000-0003-1096-5044
Michel SalzetFrom the ‡Univ. Lille, Inserm, U-1192 - Laboratoire Protéomique, Réponse Inflammatoire et Spectrométrie de Masse-PRISM, F-59000 Lille, France; Michel.salzet@univ-lille1.fr.ORCID 0000-0003-4318-0817
Inserm · FRInstitute of Chemistry of the Slovak Academy of Sciences · SKUniversité Claude Bernard Lyon 1 · FRAmerican University of Beirut · LBSlovak Academy of Sciences · SK

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

The therapeutic use of RhoA inhibitors (RhoAi) has been experimentally tested in spinal cord injury (SCI). In order to decipher the underlying molecular mechanisms involved in such a process, an

Indexed as

Analysis of VarianceAnimalsAxonsCells, CulturedDisease Models, AnimalEnzyme InhibitorsGanglia, SpinalLocomotionNeuronal OutgrowthProteomicsRatsRegenerationrho GTP-Binding ProteinsSpinal Cord InjuriesSynaptic VesiclesTacrolimusEnzyme InhibitorsRhoA protein, ratrho GTP-Binding ProteinsTacrolimusTranscription Factors

Identifiers

PMID28659490
PMCPMC5546194
OpenAlexW2726479974

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.