Evidence map›Paper›PMID 28659484›Full record

ArticleJournal of virology2017

Case-Control Comparison of Enteric Viromes in Captive Rhesus Macaques with Acute or Idiopathic Chronic Diarrhea.

Beatrix Kapusinszky, Amir Ardeshir, Usha Mulvaney, Xutao Deng, Eric Delwart

Open access · bronzeAbstract read
In one paragraph

Article in Journal of virology, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 43 papers.

0numbers the graph read from it
0cells of the map it votes in
43citing papers in PubMed
4.2field-weighted citation impact, top 5% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

43 citing papers in PubMed, 60 citations in OpenAlex.

  1. Article
  2. Article
  3. A review of chronic enterocolitis of rhesus macaques (Frontiers in veterinary science · 2026
    Review
  4. Article
  5. Review
  6. Article
  7. Article
  8. Article
  9. Article
  10. Article
  11. Article
  12. Article
  13. Article
  14. Article
  15. Article
  16. Article
  17. Review
  18. Article
  19. Article
  20. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors at 3 institutions in 1 country.

Beatrix KapusinszkyBlood Systems Research Institute, San Francisco, California, USA.
Amir ArdeshirCalifornia National Primate Research Center, School of Veterinary Medicine, University of California at Davis, Davis, California, USA.
Usha MulvaneyBlood Systems Research Institute, San Francisco, California, USA.
Xutao DengBlood Systems Research Institute, San Francisco, California, USA.
Eric DelwartBlood Systems Research Institute, San Francisco, California, USA delwarte@medicine.ucsf.edu.ORCID http://orcid.org/0000-0002-6296-4484
University of California, San Francisco · USBlood Systems Research Institute · USUniversity of California, Davis · US

Funding

National Institute on Aging (NIA) ColonyP51OD011107 · OD · UNIVERSITY OF CALIFORNIA AT DAVIS · PI Simon J. Atkinson · 2012 to 2026
$191.5M
Viral etiology of idiopathic chronic diarrhea in rhesus macaquesR01AI123376 · NIAID · VITALANT · PI DELWART, ERIC L · 2016 to 2019
$2.0M
NIAID NIH HHS R01 AI123376NIH HHS P51 OD011107
6 · The paper itself

Abstract

Diarrhea is the major cause of non-research-associated morbidity and mortality affecting the supply of rhesus macaques and, potentially, their responses to experimental treatments. Idiopathic chronic diarrhea (ICD) in rhesus macaques also resembles ulcerative colitis, one form of human inflammatory bowel disease. To test for viral etiologies, we characterized and compared the fecal viromes from 32 healthy animals, 31 animals with acute diarrhea, and 29 animals with ICD. The overall fractions of eukaryotic viral reads were 0.063% for the healthy group, 0.131% for the acute-diarrhea group, and 0.297% for the chronic-diarrhea group. Eukaryotic viruses belonging to 6 viral families, as well as numerous circular Rep-encoding single-stranded DNA (CRESS DNA) viral genomes, were identified. The most commonly detected sequences were from picornaviruses, making up 59 to 88% of all viral reads, followed by 9 to 17% for CRESS DNA virus sequences. The remaining 5 virus families,

Indexed as

Macaca mulattaAnimalsBiodiversityChronic DiseaseCoinfectionDiarrheaFecesPrimate DiseasesVirus DiseasesVirusesCRESS-DNAenteric disease etiologyenterovirusidiopathic diarrheaparvovirusrhesus macaquessapelovirus

Identifiers

PMID28659484
PMCPMC5571273
OpenAlexW2726354518

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.