Evidence map›Paper›PMID 28659464›Full record

ArticleJournal of neurophysiology2017

Impact of glutamatergic and serotonergic neurotransmission on diaphragm muscle activity after cervical spinal hemisection.

Carlos B Mantilla, Heather M Gransee, Wen-Zhi Zhan, Gary C Sieck

Open access · bronzeAbstract read
In one paragraph

Article in Journal of neurophysiology, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 12 papers.

0numbers the graph read from it
0cells of the map it votes in
12citing papers in PubMed
1.1field-weighted citation impact, top 27% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

12 citing papers in PubMed, 15 citations in OpenAlex.

  1. Article
  2. Review
  3. Article
  4. Article
  5. Article
  6. Article
  7. Article
  8. Spinal cord injury and diaphragm neuromotor control.Expert review of respiratory medicine · 2020
    Review
  9. Article
  10. Review
  11. Article
  12. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors at 1 institution in 1 country.

Carlos B MantillaDepartment of Anesthesiology and Perioperative Medicine, Mayo Clinic, Rochester, Minnesota; and mantilla.carlos@mayo.edu.
Heather M GranseeDepartment of Anesthesiology and Perioperative Medicine, Mayo Clinic, Rochester, Minnesota; and.
Wen-Zhi ZhanDepartment of Physiology and Biomedical Engineering, Mayo Clinic, Rochester, Minnesota.
Gary C SieckDepartment of Anesthesiology and Perioperative Medicine, Mayo Clinic, Rochester, Minnesota; and.
Mayo Clinic · US

Funding

Recovery of Respiratory Function After Spinal Cord InjuryR01HL096750 · NHLBI · MAYO CLINIC ROCHESTER · PI MANTILLA, CARLOS B, SIECK, GARY C. · 2010 to 2017
$4.9M
NHLBI NIH HHS R01 HL096750
6 · The paper itself

Abstract

Incomplete cervical spinal cord hemisection at C2 (SH) disrupts descending excitatory drive to phrenic motoneurons, paralyzing the ipsilateral diaphragm muscle. Spontaneous recovery over time is associated with increased phrenic motoneuron expression of glutamatergic

Indexed as

Synaptic TransmissionAnimalsDiaphragmExcitatory Amino Acid AntagonistsMaleMotor NeuronsMuscle ContractionPhrenic NerveRatsRats, Sprague-DawleyReceptors, N-Methyl-D-AspartateReceptors, SerotoninSerotonin AntagonistsSpinal CordSpinal Cord InjuriesExcitatory Amino Acid AntagonistsReceptors, N-Methyl-D-AspartateReceptors, SerotoninSerotonin Antagonistsd-AP5ketanserinneurotransmitterrespirationspinal cord injury

Identifiers

PMID28659464
PMCPMC5596137
OpenAlexW2733414751

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.