Evidence map›Paper›PMID 28659287›Full record

ArticleAmerican journal of physiology. Cell physiology2017

Reduced SCD1 activity alters markers of fatty acid reesterification, glyceroneogenesis, and lipolysis in murine white adipose tissue and 3T3-L1 adipocytes.

Steven M Dragos, Karl F Bergeron, Frédérik Desmarais, Katherine Suitor, David C Wright, Catherine Mounier, David M Mutch

Open access · bronzeAbstract read
In one paragraph

Article in American journal of physiology. Cell physiology, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 17 papers.

0numbers the graph read from it
0cells of the map it votes in
17citing papers in PubMed
1.2field-weighted citation impact, top 21% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

17 citing papers in PubMed, 34 citations in OpenAlex.

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  2. International journal of medical sciences · 2026
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 2 institutions in 1 country.

Steven M DragosDepartment of Human Health & Nutritional Sciences, University of Guelph, Guelph, Ontario, Canada; and.
Karl F BergeronDépartement des sciences biologiques et centre de recherche BioMed, Université du Québec à Montréal, Montreal, Quebec, Canada.ORCID http://orcid.org/0000-0002-7215-9104
Frédérik DesmaraisDépartement des sciences biologiques et centre de recherche BioMed, Université du Québec à Montréal, Montreal, Quebec, Canada.
Katherine SuitorDepartment of Human Health & Nutritional Sciences, University of Guelph, Guelph, Ontario, Canada; and.
David C WrightDepartment of Human Health & Nutritional Sciences, University of Guelph, Guelph, Ontario, Canada; and.
Catherine MounierDépartement des sciences biologiques et centre de recherche BioMed, Université du Québec à Montréal, Montreal, Quebec, Canada.
David M MutchDepartment of Human Health & Nutritional Sciences, University of Guelph, Guelph, Ontario, Canada; and dmutch@uoguelph.ca.
University of Guelph · CAUniversité du Québec à Montréal · CA

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

White adipose tissue (WAT) has a critical role in lipid handling. Previous work demonstrated that SCD1 is an important regulator of WAT fatty acid (FA) composition; however, its influence on the various interconnected pathways influencing WAT lipid handling remains unclear. Our objective was to investigate the role of SCD1 on WAT lipid handling using

Indexed as

3T3-L1 CellsAdipose Tissue, WhiteAnimalsBiomarkersEnzyme ActivationEsterificationFatty AcidsGene Expression Regulation, EnzymologicGlycerophosphatesLipid MetabolismLipolysisMaleMiceMice, Inbred C57BLMice, KnockoutStearoyl-CoA Desaturasealpha-glycerophosphoric acidBiomarkersFatty AcidsGlycerophosphatesScd1 protein, mouseStearoyl-CoA Desaturaseadipocytesepididymal adipose tissueinguinal adipose tissueSCD1 inhibitorSCD1−/− mice

Identifiers

PMID28659287
PMCPMC5625094
OpenAlexW2727856377

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.