ArticleCell reports2017
A Critical Analysis of the Role of SNARE Protein SEC22B in Antigen Cross-Presentation.
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In one paragraph
Article in Cell reports, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 32 papers.
0numbers the graph read from it
0cells of the map it votes in
32citing papers in PubMed
–field-weighted citation impact
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
32 citing papers in PubMed.
- Sec22b and Stx4 Depletion Has No Major Effect on Cross-Presentation of PLGA Microsphere-Encapsulated Antigen and a Synthetic Long Peptide In Vitro.Journal of immunology (Baltimore, Md. : 1950) · 2023Article
- Sec22b regulates phagosome maturation by promoting ORP8-mediated lipid exchange at endoplasmic reticulum-phagosome contact sites.Communications biology · 2023Article
- Recent progress in type 1 classical dendritic cell cross-presentation - cytosolic, vacuolar, or both?Current opinion in immunology · 2023Review
- Non-muscle-invasive bladder cancer molecular subtypes predict differential response to intravesical Bacillus Calmette-Guérin.Science translational medicine · 2023Article
- High Bacillary Burden and the ESX-1 Type VII Secretion System Promote MHC Class I Presentation by Mycobacterium tuberculosis-Infected Macrophages to CD8 T Cells.Journal of immunology (Baltimore, Md. : 1950) · 2023Article
- The evolving biology of cross-presentation.Seminars in immunology · 2023Review
- Pathways of MHC I cross-presentation of exogenous antigens.Seminars in immunology · 2023Review
- DCs at the center of help: Origins and evolution of the three-cell-type hypothesis.The Journal of experimental medicine · 2022Article
- Mechanisms of cellular and humoral immunity through the lens of VLP-based vaccines.Expert review of vaccines · 2022Review
- Spotlight on TAP and its vital role in antigen presentation and cross-presentation.Molecular immunology · 2022Review
- Vaccine adjuvants to engage the cross-presentation pathway.Frontiers in immunology · 2022Review
- TAP dysfunction in dendritic cells enables noncanonical cross-presentation for T cell priming.Nature immunology · 2021Article
- RNA-seq of human T cells after hematopoietic stem cell transplantation identifiesScience translational medicine · 2021Article
- Genetic models of human and mouse dendritic cell development and function.Nature reviews. Immunology · 2021Review
- The role of dendritic cells in cancer and anti-tumor immunity.Seminars in immunology · 2021Review
- Cross-presentation of exogenous antigens on MHC I molecules.Current opinion in immunology · 2020Review
- Endoplasmic Reticulum-Associated Degradation-Dependent Processing in Cross-Presentation and Its Potential for Dendritic Cell Vaccinations: A Review.Pharmaceutics · 2020Review
- The GTPase Rab39a promotes phagosome maturation into MHC-I antigen-presenting compartments.The EMBO journal · 2020Article
- Vaccine-Induced CD8Frontiers in immunology · 2020Review
- IRAP Endosomes Control Phagosomal Maturation in Dendritic Cells.Frontiers in cell and developmental biology · 2020Article
Corrections and comments
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Authors and funding
15 authors.
S Julia WuProgram in Immunology, University of Michigan Medical School, Ann Arbor, MI 48109, USA; Medical Scientist Training Program, University of Michigan Medical School, Ann Arbor, MI 48109, USA.
Yashar S NiknafsMedical Scientist Training Program, University of Michigan Medical School, Ann Arbor, MI 48109, USA; Cellular and Molecular Biology Program, University of Michigan Medical School, Ann Arbor, MI 48109, USA.
Stephanie H KimProgram in Immunology, University of Michigan Medical School, Ann Arbor, MI 48109, USA; Medical Scientist Training Program, University of Michigan Medical School, Ann Arbor, MI 48109, USA.
Katherine Oravecz-WilsonDivision of Hematology/Oncology, Department of Internal Medicine, Michigan Medicine, Ann Arbor, MI 48109, USA.
Cynthia ZajacDivision of Hematology/Oncology, Department of Internal Medicine, Michigan Medicine, Ann Arbor, MI 48109, USA.
Tomomi ToubaiDivision of Hematology/Oncology, Department of Internal Medicine, Michigan Medicine, Ann Arbor, MI 48109, USA.
Yaping SunDivision of Hematology/Oncology, Department of Internal Medicine, Michigan Medicine, Ann Arbor, MI 48109, USA.
Jayendra PrasadDivision of Hematology/Oncology, Department of Internal Medicine, Michigan Medicine, Ann Arbor, MI 48109, USA.
Daniel PeltierDivision of Pediatric Hematology/Oncology, Department of Pediatrics and Communicable Diseases, Michigan Medicine, Ann Arbor, MI 48109, USA.
Hideaki FujiwaraDivision of Hematology/Oncology, Department of Internal Medicine, Michigan Medicine, Ann Arbor, MI 48109, USA.
Israel HedigDivision of Hematology/Oncology, Department of Internal Medicine, Michigan Medicine, Ann Arbor, MI 48109, USA.
Nathan D MathewsonDana Farber Cancer Institute, Harvard University, Cambridge, MA 02215, USA.
Rami KhoriatyDivision of Hematology/Oncology, Department of Internal Medicine, Michigan Medicine, Ann Arbor, MI 48109, USA.
David GinsburgDivision of Hematology/Oncology, Department of Internal Medicine, Michigan Medicine, Ann Arbor, MI 48109, USA; Department of Human Genetics, University of Michigan Medical School, Ann Arbor, MI 48109, USA; Howard Hughes Medical Institute, University of Michigan, Ann Arbor, MI 48109, USA; Life Sciences Institute, University of Michigan, Ann Arbor, MI 48109, USA.
Pavan ReddyProgram in Immunology, University of Michigan Medical School, Ann Arbor, MI 48109, USA; Division of Hematology/Oncology, Department of Internal Medicine, Michigan Medicine, Ann Arbor, MI 48109, USA. Electronic address: reddypr@med.umich.edu.
Funding
MICHIGAN MEDICAL SCIENTIST TRAINING PROGRAMT32GM007863 · NIGMS · UNIVERSITY OF MICHIGAN AT ANN ARBOR · PI COLLINS, KATHLEEN L. · 1985 to 2024
$38.3MCELLULAR AND MOLECULAR BIOLOGY AT MICHIGANT32GM007315 · NIGMS · UNIVERSITY OF MICHIGAN AT ANN ARBOR · PI PUTHENVEEDU, MANOJKUMAR A · 1985 to 2021
$12.8MTraining Program in Molecular HematologyT32HL007622 · NHLBI · UNIVERSITY OF MICHIGAN AT ANN ARBOR · PI SUNG WON CHOI, Jordan A. Shavit · 1986 to 2026
$9.2MThe Molecular Genetics of HemostasisR35HL135793 · NHLBI · UNIVERSITY OF MICHIGAN AT ANN ARBOR · PI GINSBURG, DAVID · 2017 to 2023
$4.1MTargeting antigen presentation to enhance GVL responses after Bone Marrow TransplR01HL090775 · NHLBI · UNIVERSITY OF MICHIGAN AT ANN ARBOR · PI REDDY, PAVAN · 2008 to 2016
$3.4MCellular and molecular mechanisms of target tissue resistance for mitigating GVHD severityR01CA203542 · NCI · UNIVERSITY OF MICHIGAN AT ANN ARBOR · PI REDDY, PAVAN · 2016 to 2020
$2.4MDevelopment of novel strategy for treatment of steroid refractory GVHDR01HL128046 · NHLBI · UNIVERSITY OF MICHIGAN AT ANN ARBOR · PI REDDY, PAVAN · 2015 to 2019
$2.1MRole of noncoding RNA in Regulating GVHDR01CA173878 · NCI · UNIVERSITY OF MICHIGAN AT ANN ARBOR · PI REDDY, PAVAN · 2013 to 2017
$1.6MThe Evolution of the Mammalian SEC23 Paralogs and the Molecular Pathogenesis of Congenital Dyserythropoietic Anemia type IIK08HL128794 · NHLBI · UNIVERSITY OF MICHIGAN AT ANN ARBOR · PI KHORIATY, RAMI · 2015 to 2019
$812kNCI NIH HHS R01 CA173878NCI NIH HHS R01 CA203542NHLBI NIH HHS K08 HL128794NHLBI NIH HHS R01 HL090775NHLBI NIH HHS R01 HL128046NHLBI NIH HHS R35 HL135793NHLBI NIH HHS T32 HL007622NIGMS NIH HHS T32 GM007315NIGMS NIH HHS T32 GM007863
Abstract
Cross-presentation initiates immune responses against tumors and viral infections by presenting extracellular antigen on MHC I to activate CD8
Indexed as
AnimalsAntigen PresentationCross-PrimingMiceMice, TransgenicR-SNARE ProteinsR-SNARE ProteinsSec22B protein, humancross-presentationdendritic celloff-target effectRNA-seqSEC22BSNARE protein
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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.