ArticleVirulence2017
Dectin-1 plays an important role in host defense against systemic Candida glabrata infection.
Article in Virulence, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 30 papers.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
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Who cites it
30 citing papers in PubMed, 47 citations in OpenAlex.
- Immunological fitness of echinocandin-resistantVirulence · 2026Article
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- Dectin-1 and dectin-2 drive protection againstFrontiers in immunology · 2025Article
- Dectin-1 participates in β-glucan- or PMA-induced neutrophil extracellular trap formation during antifungal defense.American journal of translational research · 2025Article
- Review
- Complement receptor 3-dependent engagement byOpen biology · 2024Article
- More than Just Protein Degradation: The Regulatory Roles and Moonlighting Functions of Extracellular Proteases Produced by Fungi Pathogenic for Humans.Journal of fungi (Basel, Switzerland) · 2023Review
- Genetic Susceptibility to Fungal Infections.Advanced biomedical research · 2023Review
- Histone Acetylation Regulator Gcn5 Mediates Drug Resistance and Virulence of Candida glabrata.Microbiology spectrum · 2022Article
- Role of Vaginal Mucosa, Host Immunity and Microbiota in Vulvovaginal Candidiasis.Pathogens (Basel, Switzerland) · 2022Review
- Scavenger receptors in host defense: from functional aspects to mode of action.Cell communication and signaling : CCS · 2022Review
- Magnesium impairs Candida albicans immune evasion by reduced hyphal damage, enhanced β-glucan exposure and altered vacuole homeostasis.PloS one · 2022Article
- InvestigatingJournal of fungi (Basel, Switzerland) · 2021Article
- Neutrophils require SKAP2 for reactive oxygen species production following C-type lectin andiScience · 2021Article
- The isolation and identification of Candida glabrata from avian species and a study of the antibacterial activities of Chinese herbal medicine in vitro.Poultry science · 2021Article
- Computational prediction method to decipher receptor-glycoligand interactions in plant immunity.The Plant journal : for cell and molecular biology · 2021Article
- Immune Sensing ofJournal of fungi (Basel, Switzerland) · 2021Review
- Dependence on Mincle and Dectin-2 Varies With MultipleFrontiers in microbiology · 2021Article
- Microbial Phagocytic Receptors and Their Potential Involvement in Cytokine Induction in Macrophages.Frontiers in immunology · 2021Review
- Thermotolerance in the pathogen Cryptococcus neoformans is linked to antigen masking via mRNA decay-dependent reprogramming.Nature communications · 2019Article
Corrections and comments
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Authors and funding
12 authors at 4 institutions in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Candida glabrata is the second most common pathogen of severe candidiasis in immunocompromised hosts, following C. albicans. Although C. glabrata and C. albicans belong to the same genus, they are phylogenetically distinct. C-type lectin receptors (CLRs), acting as pattern-recognition receptors (PRRs), play critical roles in host defense against C. albicans infections. However, our understanding of the specific roles of CLRs in host defense against C. glabrata is limited. Here, we explored the potential roles of the C-type lectins Dectin-1 and Dectin-2 in host defense against C. glabrata. We found that both Dectin-1-deficient mice (Dectin-1
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.