ArticleArchives of endocrinology and metabolism
Multifocal oral melanoacanthoma associated with Addison's disease and hyperthyroidism: a case report.
Article in Archives of endocrinology and metabolism. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 6 papers.
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Who cites it
6 citing papers in PubMed, 10 citations in OpenAlex.
- A simultaneous presentation of uncommon, pigmented lesions: Oral melanoacanthoma and moderate oral epithelial dysplasia.Canadian journal of dental hygiene : CJDH = Journal canadien de l'hygiene dentaire : JCHD · 2025Article
- New Approach to Addison Disease: Oral Manifestations Due to Endocrine Dysfunction and Comorbidity Burden.Diagnostics (Basel, Switzerland) · 2022Review
- Article
- A Unique Presentation of Gingival Melanoacanthoma: Case Report and Review of Literature.Cureus · 2020Article
- Clinical and histopathological study of the oral multifocal melanoacanthoma: A case report.Journal of clinical and experimental dentistry · 2019Article
- A rare case of oral melanoacanthoma.Journal of oral and maxillofacial pathology : JOMFPArticle
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Authors and funding
6 authors at 1 institution in 1 country.
Funding
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Abstract
Oral melanoacanthoma is a mucocutaneous, pigmented, rare, benign, and probably reactive lesion. This paper reports for the first time in the literature a case of multifocal oral melanoacanthoma in a patient diagnosed with Addison's disease and concomitant Graves' disease with hyperthyroidism. The patient presented with oral pigmented lesions, which were hypothesized to be mucosal pigmentation associated with Addison's disease. Due to their unusual clinical pattern, these oral lesions were biopsied and diagnosed as oral melanoacanthoma on histopathology and immunohistochemistry for HMB-45. At the moment of this report, the patient was being treated for her systemic conditions, but the lesions had not regressed. Reactive hyperpigmentation of the skin and mucous membranes may be found in Addison's disease and hyperthyroidism. This case reinforces the hypothesis of a reactive nature for oral melanoacanthoma and highlights the need for investigation of endocrine disorders in patients with multifocal oral melanoacanthoma.
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