Evidence map›Paper›PMID 28658347›Full record

ArticleArchives of endocrinology and metabolism2017

Circulating omentin-1 might be associated with metabolic health status in different phenotypes of body size.

Shahab Alizadeh, Khadijeh Mirzaei, Chonur Mohammadi, Seyed Ali Keshavarz, Zhila Maghbooli

Open access · diamondAbstract read
In one paragraph

Article in Archives of endocrinology and metabolism, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 15 papers, 3 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
15citing papers in PubMed, 3 pooled it
1.6field-weighted citation impact, top 17% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

15 citing papers in PubMed, 3 syntheses or guidelines pooled it, 28 citations in OpenAlex.

  1. Pooled it
  2. Pooled it
  3. Pooled it
  4. Low Circulating Levels of Omentin-1 and Irisin in Type 2 Diabetes Mellitus Patients with Metabolic-Associated Fatty Liver Disease.The Turkish journal of gastroenterology : the official journal of Turkish Society of Gastroenterology · 2025
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  13. Study on Omentin-1 and miR-502-3p in osteoporotic fracture.Journal of musculoskeletal & neuronal interactions · 2021
    Article
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors at 2 institutions in 1 country.

Shahab AlizadehOsteoporosis Research Center, Endocrinology and Metabolism Clinical Sciences Institute, Tehran University of Medical Sciences (TUMS), Tehran, Iran.
Khadijeh MirzaeiDepartment of Community Nutrition, School of Nutritional Sciences and Dietetics, TUMS, Tehran, Iran.
Chonur MohammadiOsteoporosis Research Center, Endocrinology and Metabolism Clinical Sciences Institute, Tehran University of Medical Sciences (TUMS), Tehran, Iran.
Seyed Ali KeshavarzDepartment of Clinical Nutrition, School of Nutritional Sciences and Dietetics, TUMS, Tehran, Iran.
Zhila MaghbooliOsteoporosis Research Center, Endocrinology and Metabolism Clinical Sciences Institute, Tehran University of Medical Sciences (TUMS), Tehran, Iran.
Tehran University of Medical Sciences · IRIran University of Medical Sciences · IR

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

objectiveAdipokines are mediators of body composition and are involved in obesity complications. This study aimed to assess the association of circulating omentin-1, vaspin, and RBP-4 with body composition indices and metabolic health status (MHS) in different phenotypes of body size. SUBJECTS AND

methodsA total of 350 subjects were included in the current cross-sectional study. Body composition was measured using a body composition analyzer, and serum concentrations of omentin-1, vaspin, and RBP-4 were assessed by ELISA kits.

resultsCirculating omentin-1 was significantly (OR = 1.81, 95% CI: 1.00-1.91, P = 0.01) and marginally (OR = 1.63, 95%CI: 1.00-1.75, P = 0.06) associated with MHS in the overweight and obese subjects, respectively. But no association was seen between omentin-1 and MHS in normal-weight subjects. Serum levels of vaspin and RBP-4 were not correlated with MHS. Furthermore, a significant positive correlation was observed between circulating omentin-1 and body mass index (BMI) as well as fat percentage (P = 0.02) in the MHS group. Serum vaspin concentrations were not related to body composition components in both groups. In addition, in the MHS group, circulating RBP-4 was positively correlated with fat percentage and fat mass (FM) (p < 0.0001) and was negatively correlated with fat-free mass (FFM) and total body water (TBW) (p < 0.0001). In contrast, in the metabolically unhealthy group, RBP-4 was negatively correlated with fat percentage, FM, and BMI (p < 0.0001) and was positively correlated with FFM and TBW (p < 0.0001).

conclusionsThis study showed that circulating levels of omentin-1 are useful predictors of metabolic health status in overweight and obese people.

Indexed as

Body CompositionBody SizeAdultBody Mass IndexCross-Sectional StudiesCytokinesEnzyme-Linked Immunosorbent AssayFemaleGPI-Linked ProteinsHumansLectinsObesityPhenotypeRetinol-Binding Proteins, PlasmaSerpinsCytokinesGPI-Linked ProteinsITLN1 protein, humanLectinsRBP4 protein, humanRetinol-Binding Proteins, PlasmaSERPINA12 protein, humanSerpins

Identifiers

PMID28658347
PMCPMC10522062
OpenAlexW2725234817

What OpenQuestion holds

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LicenceCC BY
Read underepoch 390

Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.