Observational studyMedicine2017
A cross-sectional study on the associations of insulin resistance with sex hormone, abnormal lipid metabolism in T2DM and IGT patients.
Observational study in Medicine, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 16 papers.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
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Who cites it
16 citing papers in PubMed, 33 citations in OpenAlex.
- The relationship between abdominal fat and sleep quality after combined exercise in patients with type 2 diabetes mellitus.Frontiers in endocrinology · 2025Trial
- Pathogenesis of impaired glucose tolerance in rats based on transcriptome analysis.Scientific reports · 2025Article
- Unveiling Gestational Diabetes: An Overview of Pathophysiology and Management.International journal of molecular sciences · 2025Review
- Hypoglycemic effect of peony flowers polyphenols based on gut microbiota and metabolomics.Frontiers in nutrition · 2025Article
- Effect of eugenol on lipid profile, oxidative stress, sex hormone, liver injury, ovarian failure, and expression of COX-2 and PPAR-α genes in a rat model of diabetes.Molecular biology reports · 2023Article
- Combined Effects ofNutrients · 2023Article
- Gender Differences and Cardiometabolic Risk: The Importance of the Risk Factors.International journal of molecular sciences · 2023Review
- Adverse effects of type 2 diabetes mellitus on ovarian reserve and pregnancy outcomes during the assisted reproductive technology process.Frontiers in endocrinology · 2023Article
- FSH may mediate the association between HbA1c and bone turnover markers in postmenopausal women with type 2 diabetes.Journal of bone and mineral metabolism · 2022Article
- Accelerated Ovarian Aging Among Type 2 Diabetes Patients and Its Association With Adverse Lipid Profile.Frontiers in endocrinology · 2022Article
- Combined effects of progesterone and SOCS3 DNA methylation on T2DM: a case-control study.Clinical epigenetics · 2021Article
- Review
- Agriophyllum Oligosaccharides Ameliorate Diabetic Insulin Resistance Through INS-R/IRS/Glut4-Mediated Insulin Pathway in db/db Mice and MIN6 Cells.Frontiers in pharmacology · 2021Article
- Sex differences on adipose tissue remodeling: from molecular mechanisms to therapeutic interventions.Journal of molecular medicine (Berlin, Germany) · 2020Review
- Association between triclocarban and triclosan exposures and the risks of type 2 diabetes mellitus and impaired glucose tolerance in the National Health and Nutrition Examination Survey (NHANES 2013-2014).Environment international · 2020Article
- Serum visfatin concentration and its relationship with sex hormones in obese Saudi women.International journal of health sciencesArticle
Corrections and comments
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Authors and funding
10 authors at 1 institution in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Type 2 diabetes mellitus (T2DM) is a long-term metabolic disorder. It is characterized by hyperglycemia, insulin resistance (IR), and relative impairment in insulin secretion. IR plays a major role in the pathogenesis of T2DM. Many previous studies have investigated the relationship between estrogen, androgen, and obesity, but few focused on the relationship between sex hormones, abnormal lipid metabolism, and IR. The goal for the present study was to identify the association of IR with sex hormone, abnormal lipid metabolism in type 2 diabetes, and impaired glucose tolerance (IGT) patients.In total 13,400 participants were analyzed based on the results of the glucose tolerance test. Using a cross-sectional study, we showed the relationship between IR and the level of sex hormones among 3 different glucose tolerance states: normal control people, IGT, and T2DM patients. We also analyzed the relationship between IR and abnormal lipid metabolism.Significantly, luteinizing, progesterone, estradiol, prolactin, and follicle-stimulating hormone levels decreased in T2DM and IGT patients compared with those in normal control people. The association between IR and lipid metabolism disorders in T2DM and IGT patients was also observed.Our clinical findings may offer new insights into understanding the mechanism of metabolic disorders and in new therapeutic methods for the treatment of the prevalence of type 2 diabetes.
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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.