Evidence map›Paper›PMID 28657917›Full record

Observational studyAmerican journal of physical medicine & rehabilitation2017

Patient Registry of Spasticity Care World: Data Analysis Based on Physician Experience.

Alberto Esquenazi, Stella Lee, Nathaniel Mayer, Roser Garreta, Atul Patel, Elie Elovic, Stephen Koelbel, Gerard Francisco, Iris Reuter, PROS World Group

Abstract readMulticenter StudyObservational Study
In one paragraph

Observational study in American journal of physical medicine & rehabilitation, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 9 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
9citing papers in PubMed, 1 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

9 citing papers in PubMed, 1 synthesis or guideline pooled it.

  1. Pooled it
  2. Review
  3. Review
  4. Observational
  5. Observational
  6. Article
  7. Observational
  8. Article
  9. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors.

Alberto EsquenaziFrom the MossRehab Gait and Motion Analysis Laboratory, Elkins Park, Pennsylvania (AE, SL, NM); Mutua Terrassa University Hospital, Cataluna, Spain (RG); Kansas City Bone and Joint Clinic, Overland Park, Kansas (AP); Physical Medicine and Rehabilitation, Reno, Nevada (EE); Braintree Rehabilitation Hospital, Braintree, Massachusetts (SK); University of Texas Health Science Center and TIRR Memorial Hermann, Houston, Texas (GF); and Justus-Liebig-Universität Gießen, Gießen, Hesse, Germany (IR).
Stella Lee
Nathaniel Mayer
Roser Garreta
Atul Patel
Elie Elovic
Stephen Koelbel
Gerard Francisco
Iris Reuter
PROS World Group

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

objectiveThe aim of the study was to report physician experience-based "real-world" treatment patterns with botulinum toxin type A in patients with stroke and traumatic brain injury.

designA prospective, multicenter, international observational registry design was used.

resultsSix hundred twenty-seven participants with stroke and 132 participants with traumatic brain injury were assessed and treated by 17 more experienced physicians and 12 less experienced physicians. Due to the limited usage of abobotulinumtoxinA Dysport and incobotulinumtoxinA Xeomin, data were reported on onabotulinumtoxinA BOTOX only. Based on physician experience, onabotulinumtoxinA doses were statistically different with larger mean doses injected by more experienced physicians in the upper limb (59.9 [39.0], P = 0.001) and in the lower limb (101.8 [69.2], P < 0.001). Treated deformities significantly differed for both upper limb and lower limb (P < 0.001). More experienced physicians showed a larger mean change in Ashworth Scale scores from baseline for the equinovarus/equinus foot and stiff knee (P = 0.001 and 0.03). Less experienced physicians showed a larger mean change in Ashworth Scale scores from baseline for the adducted thigh (P = 0.05). Less experienced physicians had statistically significant larger change in hand pain scores for clenched fist deformity treatment at follow-up compared with more experienced physicians (P = 0.01). Physician experience demonstrated a significant difference on patients reported satisfaction toward their secondary goal with higher scores for more experienced physician (P = 0.04).

conclusionsThis international registry provides clinical nuances of treatment based on physician clinical experience in a robust sample size.

Indexed as

Clinical CompetencePain MeasurementRegistriesBotulinum Toxins, Type ABrain Injuries, TraumaticFemaleGlobal HealthHumansInjections, SubcutaneousInternationalityMaleMuscle SpasticityPrognosisProspective StudiesSeverity of Illness IndexStrokeBotulinum Toxins, Type A

Identifiers

PMID28657917
PMCPMC5690312

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.