ArticleEnvironmental health perspectives2017
Humoral Immunity in Arsenic-Exposed Children in Rural Bangladesh: Total Immunoglobulins and Vaccine-Specific Antibodies.
Article in Environmental health perspectives, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 27 papers, 1 of them a synthesis that pooled it.
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Who cites it
27 citing papers in PubMed, 1 synthesis or guideline pooled it, 60 citations in OpenAlex.
- Toxic metal exposure as a possible risk factor for COVID-19 and other respiratory infectious diseases.Food and chemical toxicology : an international journal published for the British Industrial Biological Research Association · 2020Pooled it
- Prenatal nutrition supplementation and growth biomarkers in preadolescent Bangladeshi children: A birth cohort study.Maternal & child nutrition · 2022Trial
- Identifying critical windows of susceptibility to perinatal lead exposure on child serum vaccine antibody levels.American journal of epidemiology · 2025Article
- Chronic arsenic exposure and cardiometabolic biomarkers in adolescents in the MINIMat longitudinal study.Journal of trace elements in medicine and biology : organ of the Society for Minerals and Trace Elements (GMS) · 2025Article
- Heavy metal exposures in aerodigestive clinic cohort of infants with reflux or dysphagia.Scientific reports · 2025Article
- Comparison of circulating and excreted metals and of autoimmunity between two Great Plains Tribal communities.Journal of autoimmunity · 2024Article
- Review
- Spatial nonstationarity and the role of environmental metal exposures on COVID-19 mortality in New Mexico.Applied geography (Sevenoaks, England) · 2024Article
- Analysis of Prospective Genetic Indicators for Prenatal Exposure to Arsenic in Newborn Cord Blood of Using Machine Learning.Biological trace element research · 2024Article
- Anthropometric measures and arsenic methylation among pregnant women in rural northern Bangladesh.Environmental research · 2023Article
- Early Life Environmental Exposure to Cadmium, Lead, and Arsenic and Age at Menarche: A Longitudinal Mother-Child Cohort Study in Bangladesh.Environmental health perspectives · 2023Article
- The Pregnancy, Arsenic, and Immune Response (PAIR) Study in rural northern Bangladesh.Paediatric and perinatal epidemiology · 2023Article
- Urinary Arsenic Concentration and Its Relationship with Bronchial Asthma in Children from Arica, Chile.Toxics · 2022Article
- Review
- Article
- Evaluating the effects between metal mixtures and serum vaccine antibody concentrations in children: a prospective birth cohort study.Environmental health : a global access science source · 2020Article
- A prospective cohort study of in utero and early childhood arsenic exposure and infectious disease in 4- to 5-year-old Bangladeshi children.Environmental epidemiology (Philadelphia, Pa.) · 2020Article
- Exposure to low-dose arsenic in early life alters innate immune function in children.Journal of immunotoxicology · 2019Article
- Arsenic-Induced Carcinogenesis and Immune Dysregulation.International journal of environmental research and public health · 2019Review
- Arsenic exposure and serum antibody concentrations to diphtheria and tetanus toxoid in children at age 5: A prospective birth cohort in Bangladesh.Environment international · 2019Article
Corrections and comments
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Authors and funding
10 authors at 3 institutions in 3 countries.
Funding
No grant is acknowledged in the PubMed record.
Abstract
backgroundEarly-life arsenic exposure has been associated with reduced cell-mediated immunity, but little is known about its effects on humoral immunity.
objectiveWe evaluated whether prenatal and childhood arsenic exposure was associated with humoral immune function in school-aged children.
methodsChildren born in a prospective mother–child cohort in rural Bangladesh were immunized with measles, mumps, and rubella (MMR) vaccines at 9 years of age (n=525). Arsenic exposure was assessed in urine (U-As), from mothers during pregnancy and their children at 4.5 and 9 years of age. Total IgG (tIgG), tIgE, tIgA, and MMR-specific IgG concentrations were measured in plasma using immunoassays.
resultsArsenic exposure was positively associated with child tIgG and tIgE, but not tIgA. The association with tIgG was mainly apparent in boys (
conclusionsArsenic exposure increased tIgG and tIgE in plasma, and tended to decrease mumps-specific IgG in children at 9 years of age. https://doi.org/10.1289/EHP318.
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