Evidence map›Paper›PMID 28657878›Full record

ArticleThe New England journal of medicine2017

Air Pollution and Mortality in the Medicare Population.

Qian Di, Yan Wang, Antonella Zanobetti, Yun Wang, Petros Koutrakis, Christine Choirat, Francesca Dominici, Joel D Schwartz

3 registry-linked trialsAbstract read
In one paragraph

Article in The New England journal of medicine, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to 3 registered trials, which are not on this map. Cited by 611 papers, 6 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
611citing papers in PubMed, 6 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT04563052 nacompletednot on this mapstarted 2020, after this paper: background citation

Measuring Knowledge and Behavior After an Educational Program on Air Pollution as a Health Risk Reduction Strategy

TypeinterventionalSponsorVillanova UniversityRan2020 to 2021Enrolled40ConditionsAir Pollution, Risk Reduction BehaviorsArmsEducational Program on Air Pollution as a Health Risk Reduction Strategy
NCT04908917 naunknown statusnot on this mapstarted 2021, after this paper: background citation

Reducing AIR Pollution Exposure to Lower Blood PRESSURE

TypeinterventionalSponsorWayne State UniversityRan2021 to 2023Enrolled200ConditionsMild Hypertension, Air Pollution ExposureArmsPortable Air Cleaner with a HEPA Filter, Portable Air Cleaner without a HEPA Filter
NCT05900947 completednot on this mapstarted 2019, after this paper: background citation

Presence of Environmental Pollutants in Human Carotid Atherosclerotic Plaques and Their Relationship With the Plaque Phenotype and Clinical Outcomes

TypeobservationalSponsorUniversity of Campania Luigi VanvitelliRan2019 to 2023Enrolled312ConditionsAtherosclerosisArmsanalysis of carotid atherosclerotic plaque
3 · Its place in the literature

Who cites it

611 citing papers in PubMed, 6 syntheses or guidelines pooled it.

  1. Assessment of long-term exposure to traffic-related air pollution: An exposure framework.Journal of exposure science & environmental epidemiology · 2025
    Pooled it
  2. Pooled it
  3. Pooled it
  4. Pooled it
  5. Pooled it
  6. Long-Term Exposure to Low-LevelEnvironmental health perspectives · 2023
    Pooled it
  7. Article
  8. Neighborhood-Scale OACS ES&T air · 2026
    Article
  9. Article
  10. Article
  11. Review
  12. Article
  13. Article
  14. Article
  15. Article
  16. Article
  17. Article
  18. Article
  19. A Drug-Environment Interaction Between PMPharmacoepidemiology and drug safety · 2026
    Article
  20. Atmospheric stressors and kidney diseases.Nature reviews. Nephrology · 2026
    Review

551 more citing papers are in PubMed but not listed here.

4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

8 authors.

Qian DiFrom the Departments of Environmental Health (Q.D., Yan Wang, A.Z., P.K., J.D.S.) and Biostatistics (Yun Wang, C.C., F.D.), Harvard T.H. Chan School of Public Health, Boston.
Yan WangFrom the Departments of Environmental Health (Q.D., Yan Wang, A.Z., P.K., J.D.S.) and Biostatistics (Yun Wang, C.C., F.D.), Harvard T.H. Chan School of Public Health, Boston.
Antonella ZanobettiFrom the Departments of Environmental Health (Q.D., Yan Wang, A.Z., P.K., J.D.S.) and Biostatistics (Yun Wang, C.C., F.D.), Harvard T.H. Chan School of Public Health, Boston.
Yun WangFrom the Departments of Environmental Health (Q.D., Yan Wang, A.Z., P.K., J.D.S.) and Biostatistics (Yun Wang, C.C., F.D.), Harvard T.H. Chan School of Public Health, Boston.
Petros KoutrakisFrom the Departments of Environmental Health (Q.D., Yan Wang, A.Z., P.K., J.D.S.) and Biostatistics (Yun Wang, C.C., F.D.), Harvard T.H. Chan School of Public Health, Boston.
Christine ChoiratFrom the Departments of Environmental Health (Q.D., Yan Wang, A.Z., P.K., J.D.S.) and Biostatistics (Yun Wang, C.C., F.D.), Harvard T.H. Chan School of Public Health, Boston.
Francesca DominiciFrom the Departments of Environmental Health (Q.D., Yan Wang, A.Z., P.K., J.D.S.) and Biostatistics (Yun Wang, C.C., F.D.), Harvard T.H. Chan School of Public Health, Boston.
Joel D SchwartzFrom the Departments of Environmental Health (Q.D., Yan Wang, A.Z., P.K., J.D.S.) and Biostatistics (Yun Wang, C.C., F.D.), Harvard T.H. Chan School of Public Health, Boston.

Funding

Translational Research Support CoreP30ES000002 · NIEHS · HARVARD UNIVERSITY (SCH OF PUBLIC HLTH) · PI JAIME ELIZABETH HART · 1985 to 2026
$44.6M
Statistical Methods for Analysis of Massive Genetic and Genomic Data in Cancer ResearchR35CA197449 · NCI · HARVARD UNIVERSITY D/B/A HARVARD SCHOOL OF PUBLIC HEALTH · PI XIHONG LIN · 2015 to 2026
$10.9M
Statistical Methods for the Spatio-Temporal Assessment of Social Disparities in CancerP01CA134294 · NCI · HARVARD SCHOOL OF PUBLIC HEALTH · PI HANEUSE, SEBASTIEN, HERNAN, MIGUEL · 2008 to 2017
$6.8M
Statistiscal methods for population health research on chemical mixturesR01ES012054 · NIEHS · JOHNS HOPKINS UNIVERSITY · PI DOMINICI, FRANCESCA · 2003 to 2010
$3.1M
Cardiovascular Health and Air Pollution: A National StudyR01ES024332 · NIEHS · HARVARD SCHOOL OF PUBLIC HEALTH · PI ZANOBETTI, ANTONELLA · 2015 to 2018
$2.5M
Causal Inference with Interference for Evaluating Air Quality PoliciesR01ES026217 · NIEHS · UNIVERSITY OF TEXAS AT AUSTIN · PI ZIGLER, CORWIN MATTHEW · 2016 to 2021
$2.2M
Vulnerability and Adaptation to Heat and Air Pollution in a Changing ClimateR21ES022585 · NIEHS · HARVARD SCHOOL OF PUBLIC HEALTH · PI DOMINICI, FRANCESCA · 2014 to 2015
$454k
Chronic effects of weather fluctuations: population susceptibility and adaptationR21ES024012 · NIEHS · HARVARD SCHOOL OF PUBLIC HEALTH · PI ZANOBETTI, ANTONELLA · 2014 to 2015
$445k
NCI NIH HHS P01 CA134294NCI NIH HHS R35 CA197449NIEHS NIH HHS P30 ES000002NIEHS NIH HHS R01 ES012054NIEHS NIH HHS R01 ES024332NIEHS NIH HHS R01 ES026217NIEHS NIH HHS R21 ES022585NIEHS NIH HHS R21 ES024012
6 · The paper itself

Abstract

backgroundStudies have shown that long-term exposure to air pollution increases mortality. However, evidence is limited for air-pollution levels below the most recent National Ambient Air Quality Standards. Previous studies involved predominantly urban populations and did not have the statistical power to estimate the health effects in underrepresented groups.

methodsWe constructed an open cohort of all Medicare beneficiaries (60,925,443 persons) in the continental United States from the years 2000 through 2012, with 460,310,521 person-years of follow-up. Annual averages of fine particulate matter (particles with a mass median aerodynamic diameter of less than 2.5 μm [PM

resultsIncreases of 10 μg per cubic meter in PM

conclusionsIn the entire Medicare population, there was significant evidence of adverse effects related to exposure to PM

Indexed as

MortalityAgedAir PollutantsAir PollutionCohort StudiesEnvironmental ExposureFemaleHumansMaleMedicareMortality, PrematureOzoneParticulate MatterProportional Hazards ModelsRacial GroupsRisk FactorsAir PollutantsOzoneParticulate Matter

Identifiers

PMID28657878
PMCPMC5766848

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Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.