Evidence map›Paper›PMID 28657427›Full record

ArticleMetabolic syndrome and related disorders2017

Expression of Metabolic Syndrome in Women with Severe Obesity.

James L Hopkins, Paul N Hopkins, Eliot A Brinton, Ted D Adams, Lance E Davidson, M Nazeem Nanjee, Steven C Hunt

Open access · greenAbstract read
In one paragraph

Article in Metabolic syndrome and related disorders, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 7 papers.

0numbers the graph read from it
0cells of the map it votes in
7citing papers in PubMed
0.6field-weighted citation impact, top 31% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

7 citing papers in PubMed, 17 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 3 institutions in 2 countries.

James L Hopkins1 Cardiovascular Genetics, Division of Cardiovascular Medicine, Department of Internal Medicine, University of Utah School of Medicine , Salt Lake City, Utah.
Paul N Hopkins1 Cardiovascular Genetics, Division of Cardiovascular Medicine, Department of Internal Medicine, University of Utah School of Medicine , Salt Lake City, Utah.
Eliot A Brinton2 The Utah Lipid Center and Utah Foundation for Biomedical Research , Salt Lake City, Utah.
Ted D Adams1 Cardiovascular Genetics, Division of Cardiovascular Medicine, Department of Internal Medicine, University of Utah School of Medicine , Salt Lake City, Utah.
Lance E Davidson1 Cardiovascular Genetics, Division of Cardiovascular Medicine, Department of Internal Medicine, University of Utah School of Medicine , Salt Lake City, Utah.
M Nazeem Nanjee1 Cardiovascular Genetics, Division of Cardiovascular Medicine, Department of Internal Medicine, University of Utah School of Medicine , Salt Lake City, Utah.
Steven C Hunt1 Cardiovascular Genetics, Division of Cardiovascular Medicine, Department of Internal Medicine, University of Utah School of Medicine , Salt Lake City, Utah.
University of Utah · USIntermountain Healthcare · USMasonic Foundation of Utah · US

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundThe prevalence of metabolic syndrome (MetS) generally rises with increasing adiposity, but tends to plateau at the highest levels of body mass index (BMI) with some individuals, even with severe obesity, expressing few or no components of MetS. We examined factors associated with the expression of MetS in severely obese women participating in a large observational study.

methodsAnthropometrics, including Heath equation-adjusted bioimpedance-determined fat-free mass (FFM) and fat mass (FM), lipids and related laboratory measurements, resting energy expenditure (REE), and respiratory quotient (RQ), were studied in 949 women with severe obesity.

resultsEven though the mean BMI was 45.7 kg/m

conclusionsIn women with severe obesity, higher FFM and REE were paradoxically associated with increased rather than decreased risk of MetS, while FFM-adjusted FM was unrelated to MetS.

Indexed as

AdiposityAdultBody CompositionBody Mass IndexEnergy MetabolismFemaleHumansInsulinLipidsLiverMetabolic SyndromeMiddle AgedObesity, MorbidRespiratory RateYoung AdultInsulinLipidsinsulinliver enzymesmetabolic syndromeobesity

Identifiers

PMID28657427
PMCPMC5564055
OpenAlexW2732949556

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.