Evidence map›Paper›PMID 28657303›Full record

ArticleBiochemistry2017

Cooperative RNA Folding under Cellular Conditions Arises From Both Tertiary Structure Stabilization and Secondary Structure Destabilization.

Kathleen A Leamy, Neela H Yennawar, Philip C Bevilacqua

Abstract readComparative Study
In one paragraph

Article in Biochemistry, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 35 papers.

0numbers the graph read from it
0cells of the map it votes in
35citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

35 citing papers in PubMed.

  1. Nearest Neighbor Parameters for Estimating RNA Folding Stability withbioRxiv : the preprint server for biology · 2026
    Article
  2. Thermophysical Properties of a tRNA Isodecoder.The journal of physical chemistry. B · 2026
    Article
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  9. Structure of pre-miR-31 reveals an active role in Dicer-TRBP complex processing.Proceedings of the National Academy of Sciences of the United States of America · 2023
    Article
  10. Article
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  13. Structure of pre-miR-31 reveals an active role in Dicer processing.bioRxiv : the preprint server for biology · 2023
    Article
  14. Article
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors.

Kathleen A LeamyDepartment of Chemistry, ‡Center for RNA Molecular Biology, §Huck Institutes of the Life Sciences, and ⊥Department of Biochemistry and Molecular Biology, Pennsylvania State University , University Park, Pennsylvania 16802, United States.
Neela H YennawarDepartment of Chemistry, ‡Center for RNA Molecular Biology, §Huck Institutes of the Life Sciences, and ⊥Department of Biochemistry and Molecular Biology, Pennsylvania State University , University Park, Pennsylvania 16802, United States.
Philip C BevilacquaDepartment of Chemistry, ‡Center for RNA Molecular Biology, §Huck Institutes of the Life Sciences, and ⊥Department of Biochemistry and Molecular Biology, Pennsylvania State University , University Park, Pennsylvania 16802, United States.ORCID 0000-0001-8074-3434

Funding

Overall (pp. 40-62)P41GM103485 · NIGMS · CORNELL UNIVERSITY · PI CERIONE, RICHARD A. · 2012 to 2018
$15.5M
RNA Folding and Adaptation in a Cellular ContextR01GM110237 · NIGMS · PENNSYLVANIA STATE UNIVERSITY, THE · PI BEVILACQUA, PHILIP C · 2014 to 2017
$1.1M
NIGMS NIH HHS P41 GM103485NIGMS NIH HHS R01 GM110237
6 · The paper itself

Abstract

RNA folding has been studied extensively in vitro, typically under dilute solution conditions and abiologically high salt concentrations of 1 M Na

Indexed as

Models, MolecularAlgorithmsHot TemperatureMagnesiumMolecular WeightNucleic Acid DenaturationOsmolar ConcentrationPolyethylene GlycolsProtein FoldingRNA FoldingRNA, FungalRNA StabilityRNA, Transfer, PheSaccharomyces cerevisiaeScattering, Small AngleTransition TemperatureMagnesiumPolyethylene GlycolsRNA, FungalRNA, Transfer, Phe

Identifiers

PMID28657303
PMCPMC5542450

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.