Evidence map›Paper›PMID 28657291›Full record

ArticleACS applied materials & interfaces2017

Surface PEG Grafting Density Determines Magnetic Relaxation Properties of Gd-Loaded Porous Nanoparticles for MR Imaging Applications.

Wuyuan Zhang, Jonathan Martinelli, Joop A Peters, Jacob M A van Hengst, Hans Bouwmeester, Evelien Kramer, Célia S Bonnet, Frédéric Szeremeta, Éva Tóth, Kristina Djanashvili

Abstract read
In one paragraph

Article in ACS applied materials & interfaces, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

4 citing papers in PubMed.

  1. Contrast Agents for Enhanced Bioimaging: A Comprehensive Review.Chembiochem : a European journal of chemical biology · 2026
    Review
  2. Article
  3. Article
  4. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors.

Wuyuan ZhangDepartment of Biotechnology, Delft University of Technology , Van der Maasweg 9, 2629HZ Delft, The Netherlands.
Jonathan MartinelliDepartment of Biotechnology, Delft University of Technology , Van der Maasweg 9, 2629HZ Delft, The Netherlands.
Joop A PetersDepartment of Biotechnology, Delft University of Technology , Van der Maasweg 9, 2629HZ Delft, The Netherlands.ORCID http://orcid.org/0000-0001-8503-1452
Jacob M A van HengstDepartment of Biotechnology, Delft University of Technology , Van der Maasweg 9, 2629HZ Delft, The Netherlands.
Hans BouwmeesterRIKILT Wageningen Research , Akkermaalsbos 2, 6708WB Wageningen, The Netherlands.
Evelien KramerRIKILT Wageningen Research , Akkermaalsbos 2, 6708WB Wageningen, The Netherlands.
Célia S BonnetCentre de Biophysique Moléculaire, CNRS, Rue Charles Sadron , 45071 Orléans Cedex 2, France.
Frédéric SzeremetaCentre de Biophysique Moléculaire, CNRS, Rue Charles Sadron , 45071 Orléans Cedex 2, France.
Éva TóthCentre de Biophysique Moléculaire, CNRS, Rue Charles Sadron , 45071 Orléans Cedex 2, France.
Kristina DjanashviliDepartment of Biotechnology, Delft University of Technology , Van der Maasweg 9, 2629HZ Delft, The Netherlands.ORCID http://orcid.org/0000-0003-1511-015X

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Surface PEGylation of nanoparticles designed for biomedical applications is a common and straightforward way to stabilize the materials for in vivo administration and to increase their circulation time. This strategy becomes less trivial when MRI active porous nanomaterials are concerned as their function relies on water/proton-exchange between the pores and bulk water. Here we present a comprehensive study on the effects of PEGylation on the relaxometric properties of nanozeolite LTL (dimensions of 20 × 40 nm) ion-exchanged with paramagnetic Gd

Indexed as

Metal NanoparticlesContrast MediaGadoliniumMagnetic Resonance ImagingMagneticsPolyethylene GlycolsPorosityContrast MediaGadoliniumPolyethylene GlycolsMRI contrast agentsPEGylationporous nanoparticlesrelaxivitywater exchangezeolites

Identifiers

PMID28657291
PMCPMC5520100

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.