ArticleNature communications2017
Virus-host relationships of marine single-celled eukaryotes resolved from metatranscriptomics.
Article in Nature communications, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 71 papers, 1 of them a synthesis that pooled it.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
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Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
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Who cites it
71 citing papers in PubMed, 1 synthesis or guideline pooled it, 122 citations in OpenAlex.
- Recent Advanced Technologies for the Characterization of Xenobiotic-Degrading Microorganisms and Microbial Communities.Frontiers in bioengineering and biotechnology · 2021Pooled it
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- Synergistic Effects of Viruses and Environmental Gradients on Carbon Cycling in a River Ecosystem.Biology · 2026Article
- Local microenvironments of capsomer variants in the PBCV-1.Journal of structural biology · 2025Article
- Convergent evolution of viral-like Borg archaeal extrachromosomal elements and giant eukaryotic viruses.Nature communications · 2025Article
- Revived ancient viruses from deep-sea ecosystems are biothreats by triggering gut dysbiosis.mBio · 2025Article
- Environmental transcriptomics under heat stress: Can environmental RNA reveal changes in gene expression of aquatic organisms?Molecular ecology · 2025Article
- Taxonomically distinct diatom viruses differentially impact microbial processing of organic matter.Science advances · 2025Article
- Article
- Phylogenetic proximity is a key driver of temporal succession of marine giant viruses in a five-year metagenomic time-series.ISME communications · 2025Article
- Temperature-driven biogeography of marine giant viruses infecting picoeukaryotesISME communications · 2025Article
- Prophage-encoded antibiotic resistance genes are enriched in human-impacted environments.Nature communications · 2024Article
- Time of day of infection shapes development of a eukaryotic algal-Nucleocytoviricota virocell.FEMS microbiology ecology · 2024Article
- Metatranscriptomic analysis reveals dissimilarity in viral community activity between an ice-free and ice-covered winter in Lake Erie.mSystems · 2024Article
- Unraveling the habitat preferences, ecological drivers, potential hosts, and auxiliary metabolism of soil giant viruses across China.Microbiome · 2024Article
- Active prokaryotic and eukaryotic viral ecology across spatial scale in a deep-sea brine pool.ISME communications · 2024Article
- A comprehensive overview of microbiome data in the light of machine learning applications: categorization, accessibility, and future directions.Frontiers in microbiology · 2024Review
- Article
- Phylogenetic diversity and functional potential of large and cell-associated viruses in the Bay of Bengal.mSphere · 2023Article
11 more citing papers are in PubMed but not listed here.
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
6 authors at 4 institutions in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Establishing virus-host relationships has historically relied on culture-dependent approaches. Here we report on the use of marine metatranscriptomics to probe virus-host relationships. Statistical co-occurrence analyses of dsDNA, ssRNA and dsRNA viral markers of polyadenylation-selected RNA sequences from microbial communities dominated by Aureococcus anophagefferens (Quantuck Bay, NY), and diatoms (Narragansett Bay, RI) show active infections by diverse giant viruses (NCLDVs) associated with algal and nonalgal hosts. Ongoing infections of A. anophagefferens by a known Mimiviridae (AaV) occur during bloom peak and decline. Bloom decline is also accompanied by increased activity of viruses other than AaV, including (+) ssRNA viruses. In Narragansett Bay, increased temporal resolution reveals active NCLDVs with both 'boom-and-bust' and 'steady-state infection'-like ecologies that include known as well as novel virus-host interactions. Our approach offers a method for screening active viral infections and develops links between viruses and their potential hosts in situ. Our observations further demonstrate that previously unknown virus-host relationships in marine systems are abundant.
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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.