ArticleQuality of life research : an international journal of quality of life aspects of treatment, care and rehabilitation2017
Relationship between subjective and actigraphy-measured sleep in 237 patients with metastatic colorectal cancer.
Article in Quality of life research : an international journal of quality of life aspects of treatment, care and rehabilitation, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 24 papers.
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Who cites it
24 citing papers in PubMed, 41 citations in OpenAlex.
- Trial
- Distinct sleep and rest-activity profiles according to adjuvant treatment exposure in women treated for breast cancer.The oncologist · 2026Article
- The Association Between Circadian Disruption in Core Body Temperature Rhythm and Post-Chemotherapy Sleep Disturbances in Breast Cancer Survivors.Journal of sleep research · 2026Article
- Blood Clock Correlation Distance (BloodCCD) as a novel marker to detect circadian rhythm disruption in cancer survivors with insomnia.BJC reports · 2025Article
- Comparison of subjectively and objectively measured sleep-wake patterns among patients with primary brain tumors.Neuro-oncology practice · 2024Article
- Sleep disturbance in adults with untreated primary brain tumors: prevalence and impact on quality of life.Sleep and biological rhythms · 2023Article
- Article
- Circadian rhythm disorders in patients with advanced cancer: a scoping review.Frontiers in oncology · 2023Article
- Circadian, hormonal, and sleep rhythms: effects on cancer progression implications for treatment.Frontiers in oncology · 2023Review
- A nurse-delivered intervention to reduce insomnia in cancer survivors: Study protocol for a randomized-controlled trial.Contemporary clinical trials · 2022Article
- Detecting the Effect Size of Weather Conditions on Patient-Reported Outcome Measures (PROMs).Journal of personalized medicine · 2022Article
- Comparison of objective and subjective sleep time and quality in hospitalized recipients of hematopoietic stem cell transplantation.Asia-Pacific journal of oncology nursing · 2022Article
- Review
- Adaptive Auricular Point Acupressure for Sleep Disturbance in Women with Breast Cancer: A Randomized Controlled Trial.Evidence-based complementary and alternative medicine : eCAM · 2022Article
- Circadian disruption and cancer- and treatment-related symptoms.Frontiers in oncology · 2022Review
- Actigraphy-measured rest-activity circadian rhythm disruption in patients with advanced cancer: a scoping review.Supportive care in cancer : official journal of the Multinational Association of Supportive Care in Cancer · 2021Article
- A multidisciplinary perspective on the complex interactions between sleep, circadian, and metabolic disruption in cancer patients.Cancer metastasis reviews · 2021Review
- Irregular Sleep/Wake Patterns Are Associated With Reduced Quality of Life in Post-treatment Cancer Patients: A Study Across Three Cancer Cohorts.Frontiers in neuroscience · 2021Article
- Article
- Sleep quality in hospitalized patients with advanced cancer: an observational study using self-reports of sleep and actigraphy.Supportive care in cancer : official journal of the Multinational Association of Supportive Care in Cancer · 2020Observational
Corrections and comments
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Authors and funding
9 authors at 6 institutions in 4 countries.
Funding
Abstract
objectivePatients with cancers frequently experience sleep and circadian dysfunction. To date, only a few studies have used both a questionnaire and actigraphy for concomitant evaluation of sleep and circadian function in patients with cancer. We sought to evaluate objective sleep and circadian parameters in metastatic colon cancer (MCC) patients and their associations with symptoms and quality of life (QOL).
methodsPatients reported subjective sleep problems on the EORTC QLQ-C30. Sleep and circadian parameters were calculated using a wrist-actigraph that patients wore for 72 h.
results237 Patients with MCC (mean age: 60.4 years; range: 20.7-77.6; Male/Female ratio: 1.66) participated in this cross-sectional study. Subjective sleep problems were reported by 63.4% of patients (S+). No differences in any sleep parameters (sleep efficiency, sleep latency, total sleep time, total time in bed, wake after sleep onset, activity bathyphase) were observed between S+ and S- patients. However, S+ patients displayed a significantly worse circadian function than S- patients (96.4 vs 98.1%; p = 0.005). The presence of poor subjective sleep and objective circadian dysfunction negatively affected symptoms and QOL domains (p = 0.038).
conclusionsSubjective report of sleep problems was not associated with worse objectively measured sleep parameters in patients with MCC although it was associated with disrupted circadian rest-activity rhythm and poorer QOL. These findings coincide with prior research in cancer patients in that an inconsistent relationship exists between subjective and objective sleep measurements on some sleep domains. This study supports the value of coupled evaluation of self-reported and objective measures of sleep and circadian function in cancer patients.
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