Evidence map›Paper›PMID 28656482›Full record

ArticleMolecular neurobiology2018

Gestational Hypothyroxinemia Imprints a Switch in the Capacity of Astrocytes and Microglial Cells of the Offspring to React in Inflammation.

María C Opazo, Pablo A González, Betsi D Flores, Luis F Venegas, Eduardo A Albornoz, Pablo Cisternas, Karen Bohmwald, Pamela A Nieto, Susan M Bueno, Alexis M Kalergis and 1 more

Open access · greenAbstract read
PubMed Publisher
In one paragraph

Article in Molecular neurobiology, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 6 papers.

0numbers the graph read from it
0cells of the map it votes in
6citing papers in PubMed
0.5field-weighted citation impact, top 31% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

6 citing papers in PubMed, 9 citations in OpenAlex.

  1. Article
  2. Article
  3. Article
  4. Review
  5. Article
  6. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

11 authors at 2 institutions in 1 country.

María C OpazoLaboratorio de Biología Celular y Farmacología, Facultad de Ciencias Biológicas y Facultad de Medicina, Universidad Andres Bello, Santiago, Chile.
Pablo A GonzálezLaboratorio de Biología Celular y Farmacología, Facultad de Ciencias Biológicas y Facultad de Medicina, Universidad Andres Bello, Santiago, Chile.
Betsi D FloresLaboratorio de Biología Celular y Farmacología, Facultad de Ciencias Biológicas y Facultad de Medicina, Universidad Andres Bello, Santiago, Chile.
Luis F VenegasLaboratorio de Biología Celular y Farmacología, Facultad de Ciencias Biológicas y Facultad de Medicina, Universidad Andres Bello, Santiago, Chile.
Eduardo A AlbornozLaboratorio de Biología Celular y Farmacología, Facultad de Ciencias Biológicas y Facultad de Medicina, Universidad Andres Bello, Santiago, Chile.
Pablo CisternasLaboratorio de Biología Celular y Farmacología, Facultad de Ciencias Biológicas y Facultad de Medicina, Universidad Andres Bello, Santiago, Chile.
Karen BohmwaldMillennium Institute on Immunology and Immunotherapy, Departamento de Genética Molecular y Microbiología, Facultad de Ciencias Biológicas, Pontificia Universidad Católica de Chile, Santiago, Chile.
Pamela A NietoMillennium Institute on Immunology and Immunotherapy, Departamento de Genética Molecular y Microbiología, Facultad de Ciencias Biológicas, Pontificia Universidad Católica de Chile, Santiago, Chile.
Susan M BuenoMillennium Institute on Immunology and Immunotherapy, Departamento de Genética Molecular y Microbiología, Facultad de Ciencias Biológicas, Pontificia Universidad Católica de Chile, Santiago, Chile.
Alexis M KalergisMillennium Institute on Immunology and Immunotherapy, Departamento de Genética Molecular y Microbiología, Facultad de Ciencias Biológicas, Pontificia Universidad Católica de Chile, Santiago, Chile.
Claudia A RiedelLaboratorio de Biología Celular y Farmacología, Facultad de Ciencias Biológicas y Facultad de Medicina, Universidad Andres Bello, Santiago, Chile. claudia.riedel@unab.cl.ORCID http://orcid.org/0000-0003-3784-3901
Universidad Andrés Bello · CLPontificia Universidad Católica de Chile · CL

Funding

FONDECYT 1110604FONDECYT 1130996FONDECYT 1150862FONDECYT 1161525FONDECYT POSTDOCTORADO 3130539Millenium Institute on Immunology and Immunotherapy P09/016-FNúcleo UNAB DI-741-15/N
6 · The paper itself

Abstract

Hypothyroxinemia (Hpx) is a highly frequent condition characterized by low thyroxine (T

Indexed as

AnimalsApoptosisAstrocytesCells, CulturedChemokine CXCL2FemaleGlial Fibrillary Acidic ProteinInflammationInterleukin-1betaMaleMicrogliaNitric OxideNitric Oxide Synthase Type IIPregnancyRats, Sprague-DawleyThyroxineChemokine CXCL2Cxcl2 protein, ratGlial Fibrillary Acidic ProteinInterleukin-1betaNitric OxideNitric Oxide Synthase Type IIThyroxineTissue Inhibitor of Metalloproteinase-1Tumor Necrosis Factor-alphaAstrocytesEAEGestational hypothyroxinemiaMicrogliaNeuron

Identifiers

PMID28656482
OpenAlexW2733847969

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.