Evidence map›Paper›PMID 28656475›Full record

ReviewEuropean biophysics journal : EBJ2018

Gravity and neuronal adaptation, in vitro and in vivo-from neuronal cells up to neuromuscular responses: a first model.

Florian P M Kohn, Ramona Ritzmann

Abstract readReview
In one paragraph

Review in European biophysics journal : EBJ, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 26 papers.

0numbers the graph read from it
0cells of the map it votes in
26citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

26 citing papers in PubMed.

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  12. 3D cell culture model: From ground experiment to microgravity study.Frontiers in bioengineering and biotechnology · 2023
    Review
  13. Review
  14. Single Cell in a Gravity Field.Life (Basel, Switzerland) · 2022
    Review
  15. Article
  16. Article
  17. Article
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  20. Mechanobiological Implications of Cancer Progression in Space.Frontiers in cell and developmental biology · 2021
    Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

2 authors.

Florian P M KohnDepartment of Membrane Physiology (230b), Institute of Physiology (230), University of Hohenheim, Garbenstr. 30, 70599, Stuttgart, Germany. florian.p.m.kohn@uni-hohenheim.de.
Ramona RitzmannInstitute of Sport and Sport Science, University of Freiburg, Freiburg, Germany.

Funding

Deutsches Zentrum für Luft- und Raumfahrt 50 WB 1534
6 · The paper itself

Abstract

For decades it has been shown that acute changes in gravity have an effect on neuronal systems of human and animals on different levels, from the molecular level to the whole nervous system. The functional properties and gravity-dependent adaptations of these system levels have been investigated with no or barely any interconnection. This review summarizes the gravity-dependent adaptation processes in human and animal organisms from the in vitro cellular level with its biophysical properties to the in vivo motor responses and underlying sensorimotor functions of human subjects. Subsequently, a first model for short-term adaptation of neuronal transmission is presented and discussed for the first time, which integrates the responses of the different levels of organization to changes in gravity.

Indexed as

Adaptation, PhysiologicalGravitationAnimalsHumansMusclesNeuronsAdaptationElectrophysiologyHypergravityMembrane propertiesMicrogravityNeuronal systemSensorimotor function

Identifiers

PMID28656475
PMCPMC5834568

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.