Evidence map›Paper›PMID 28656172›Full record

ArticlemSphere

Sulfide Homeostasis and Nitroxyl Intersect via Formation of Reactive Sulfur Species in

Hui Peng, Jiangchuan Shen, Katherine A Edmonds, Justin L Luebke, Anne K Hickey, Lauren D Palmer, Feng-Ming James Chang, Kevin A Bruce, Thomas E Kehl-Fie, Eric P Skaar and 1 more

Open access · goldAbstract read
In one paragraph

Article in mSphere. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 44 papers.

0numbers the graph read from it
0cells of the map it votes in
44citing papers in PubMed
4.9field-weighted citation impact, top 5% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

44 citing papers in PubMed, 76 citations in OpenAlex.

  1. Article
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  3. Unique structural and ligand-binding properties of theProceedings of the National Academy of Sciences of the United States of America · 2026
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  4. Self-bioRxiv : the preprint server for biology · 2026
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  5. Unique structural and ligand binding properties of thebioRxiv : the preprint server for biology · 2025
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  15. Para-SubstitutedMolecules (Basel, Switzerland) · 2022
    Article
  16. The Old Yellow Enzyme OfrA FostersFrontiers in microbiology · 2022
    Article
  17. Article
  18. Review
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

11 authors at 3 institutions in 1 country.

Hui PengDepartment of Chemistry, Indiana University, Bloomington, Indiana, USA.
Jiangchuan ShenDepartment of Chemistry, Indiana University, Bloomington, Indiana, USA.
Katherine A EdmondsDepartment of Chemistry, Indiana University, Bloomington, Indiana, USA.
Justin L LuebkeDepartment of Chemistry, Indiana University, Bloomington, Indiana, USA.
Anne K HickeyDepartment of Chemistry, Indiana University, Bloomington, Indiana, USA.
Lauren D PalmerDepartment of Pathology, Microbiology, and Immunology, Vanderbilt University Medical Center, Nashville, Tennessee, USA.
Feng-Ming James ChangDepartment of Chemistry, Indiana University, Bloomington, Indiana, USA.
Kevin A BruceDepartment of Biology, Indiana University, Bloomington, Indiana, USA.
Thomas E Kehl-FieDepartment of Pathology, Microbiology, and Immunology, Vanderbilt University Medical Center, Nashville, Tennessee, USA.
Eric P SkaarDepartment of Pathology, Microbiology, and Immunology, Vanderbilt University Medical Center, Nashville, Tennessee, USA.
David P GiedrocDepartment of Chemistry, Indiana University, Bloomington, Indiana, USA.ORCID 0000-0002-2342-1620
Indiana University Bloomington · USVanderbilt University Medical Center · USUniversity of Illinois Urbana-Champaign · US

Funding

Pathobiology of heme inducible transporters in Gram positive pathogensR01AI073843 · NIAID · VANDERBILT UNIVERSITY MEDICAL CENTER · PI SKAAR, ERIC P · 2009 to 2025
$5.9M
Transition Metal Homeostasis and Reactive Sulfur Species in Bacterial PathogensR35GM118157 · NIGMS · TRUSTEES OF INDIANA UNIVERSITY · PI DAVID P. GIEDROC · 2016 to 2026
$5.9M
Mechanism and function of heme-iron utilization in staphylococcal pathogenesisR01AI069233 · NIAID · VANDERBILT UNIVERSITY MEDICAL CENTER · PI SKAAR, ERIC P · 2006 to 2020
$5.6M
Overcoming nutritional immunity: Staphylococcal adaptation to host-imposed manganese and zinc starvationR01AI118880 · NIAID · UNIVERSITY OF ILLINOIS AT URBANA-CHAMPAIGN · PI KEHL-FIE, THOMAS EVERETT · 2016 to 2020
$1.9M
Defining the molecular link between zinc deficiency and pneumoniaF32AI122516 · NIAID · VANDERBILT UNIVERSITY MEDICAL CENTER · PI PALMER, LAUREN DISTERHOFT · 2016 to 2017
$113k
NIAID NIH HHS R01 AI069233NIAID NIH HHS R01 AI073843NIAID NIH HHS R01 AI118880NIGMS NIH HHS R35 GM118157
6 · The paper itself

Abstract

PubMed holds no abstract for this paper.

Indexed as

hydrogen sulfidenitric oxidenitroxylpersulfidereactive nitrogen speciesreactive sulfur speciestranscriptomics

Identifiers

PMID28656172
PMCPMC5480029
OpenAlexW2647539693

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.