Evidence map›Paper›PMID 28656102›Full record

ArticleJournal of ophthalmology2017

Treatment of Neovascular Age-Related Macular Degeneration with Anti-VEGF Agents: Predictive Factors of Long-Term Visual Outcomes.

Ana Catarina Pedrosa, Tiago Sousa, João Pinheiro-Costa, João Beato, Manuel S Falcão, Fernando Falcão-Reis, Angela Carneiro

Abstract read
In one paragraph

Article in Journal of ophthalmology, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 19 papers.

0numbers the graph read from it
0cells of the map it votes in
19citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

19 citing papers in PubMed.

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  7. Results of patients with neovascular age-related macular degeneration managed by a treat-extend-stop protocol without recurrence.Graefe's archive for clinical and experimental ophthalmology = Albrecht von Graefes Archiv fur klinische und experimentelle Ophthalmologie · 2021
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  8. Review
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  10. Voluntary Exercise Suppresses Choroidal Neovascularization in Mice.Investigative ophthalmology & visual science · 2020
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors.

Ana Catarina PedrosaDepartment of Ophthalmology, Centro Hospitalar São João, Porto, Portugal.ORCID 0000-0001-6831-5488
Tiago SousaDepartment of Sense Organs, Faculty of Medicine of the University of Porto, Porto, Portugal.
João Pinheiro-CostaDepartment of Ophthalmology, Centro Hospitalar São João, Porto, Portugal.
João BeatoDepartment of Ophthalmology, Centro Hospitalar São João, Porto, Portugal.
Manuel S FalcãoDepartment of Ophthalmology, Centro Hospitalar São João, Porto, Portugal.
Fernando Falcão-ReisDepartment of Ophthalmology, Centro Hospitalar São João, Porto, Portugal.
Angela CarneiroDepartment of Ophthalmology, Centro Hospitalar São João, Porto, Portugal.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

purposeTo evaluate the predictive factors of long-term visual outcomes in neovascular age-related macular degeneration (nAMD) treated with antivascular endothelial growth factor (anti-VEGF) agents.

methodsUnicentric retrospective review of patients with nAMD treated with anti-VEGF agents. Visual outcomes, 12 and 60 months after diagnosis, were evaluated. In an attempt to identify predictive factors of visual outcomes, multiple variables (demographic and epidemiological characteristics, angiographic and tomographic features) were analyzed, at baseline and during follow-up.

resultsOne hundred and seventeen patients were included. In multivariate analysis, baseline best-corrected visual acuity was associated with all visual endpoints at 12 and 60 months. Additionally, age, gender, number of injections, and development of subretinal fibrosis during follow-up were also significant predictors of visual outcomes at 60 months.

conclusionsSeveral factors can be useful in clinical practice as predictors of visual outcomes in response to anti-VEGF treatment of nAMD.

Identifiers

PMID28656102
PMCPMC5471580

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.