ArticleScientific reports2017
High-throughput format for the phenotyping of fungi on solid substrates.
Article in Scientific reports, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. An erratum has been issued. Cited by 19 papers.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
19 citing papers in PubMed, 33 citations in OpenAlex.
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- Isolation of a novel marineJournal of biosciences · 2025Article
- TheFrontiers in cellular and infection microbiology · 2024Article
- Impact of malt concentration in solid substrate on mycelial growth and network connectivity in Ganoderma species.Scientific reports · 2023Article
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- Endophytic fungi: hidden treasure chest of antimicrobial metabolites interrelationship of endophytes and metabolites.Frontiers in microbiology · 2023Review
- Genomic and Phenotypic Trait Variation of the Opportunistic Human Pathogen Aspergillus flavus and Its Close Relatives.Microbiology spectrum · 2022Article
- Fungal Lignocellulose Utilisation Strategies from a Bioenergetic Perspective: Quantification of Related Functional Traits Using Biocalorimetry.Microorganisms · 2022Article
- The Fungal Protein Mes1 Is Required for Morphogenesis and Virulence in the Dimorphic PhytopathogenJournal of fungi (Basel, Switzerland) · 2022Article
- Endophytic Fungi: From Symbiosis to Secondary Metabolite Communications or Vice Versa?Frontiers in plant science · 2021Review
- Naturally Occurring Phenols Modulate Vegetative Growth and Deoxynivalenol Biosynthesis inACS omega · 2020Article
- The Cell Wall Integrity Pathway Contributes to the Early Stages ofApplied and environmental microbiology · 2020Article
- Pathways of Pathogenicity: Transcriptional Stages of Germination in the Fatal Fungal PathogenmSphere · 2018Article
- Autolytic hydrolases affect sexual and asexual development of Aspergillus nidulans.Folia microbiologica · 2018Article
- Truncation of the transcriptional repressor protein Cre1 inFungal biology and biotechnology · 2018Article
Corrections and comments
- Erratum issued
Authors and funding
4 authors at 3 institutions in 2 countries.
Funding
Abstract
Filamentous fungi naturally grow on solid surfaces, yet most genetic and biochemical analyses are still performed in liquid cultures. Here, we report a multiplexing platform using high-throughput photometric continuous reading that allows parallel quantification of hyphal growth and reporter gene expression directly on solid medium, thereby mimicking natural environmental conditions. Using this system, we have quantified fungal growth and expression of secondary metabolite GFP-based reporter genes in saprophytic Aspergillus and phytopathogenic Fusarium species in response to different nutrients, stress conditions and epigenetic modifiers. With this method, we provide not only novel insights into the characteristic of fungal growth but also into the metabolic and time-dependent regulation of secondary metabolite gene expression.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.