ArticleScientific reports2017
Moving and unsinkable graphene sheets immobilized enzyme for microfluidic biocatalysis.
Article in Scientific reports, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 13 papers, 1 of them a synthesis that pooled it.
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Who cites it
13 citing papers in PubMed, 1 synthesis or guideline pooled it, 62 citations in OpenAlex.
- Use of Naringinase to Modify the Sensory Quality of Foods and Increase the Bioavailability of Flavonoids: A Systematic Review.Molecules (Basel, Switzerland) · 2025Pooled it
- Review
- Enzyme Immobilization on Nanomaterials and Their Applications.Materials (Basel, Switzerland) · 2025Review
- Recent Progress and Future Prospects of Laccase Immobilization on MOF Supports for Industrial Applications.Applied biochemistry and biotechnology · 2024Review
- Biocatalytic Performance ofMicromachines · 2024Article
- Support Materials of Organic and Inorganic Origin as Platforms for Horseradish Peroxidase Immobilization: Comparison Study for High Stability and Activity Recovery.Molecules (Basel, Switzerland) · 2024Article
- Developing Enzyme Immobilization with Fibrous Membranes: Longevity and Characterization Considerations.Membranes · 2023Review
- Review
- Graphene Oxide (GO) Materials-Applications and Toxicity on Living Organisms and Environment.Journal of functional biomaterials · 2022Review
- Enrichment and purification of red pigments from defective mulberry fruits using biotransformation in a liquid-liquid-solid three-phase system.Environmental science and pollution research international · 2021Article
- Copolymeric Hydrogel-Based Immobilization of Yeast Cells for Continuous Biotransformation of Fumaric Acid in a Microreactor.Micromachines · 2019Article
- Preparation, characterization and reusability efficacy of amine-functionalized graphene oxide-polyphenol oxidase complex for removal of phenol from aqueous phase.RSC advances · 2018Article
- Applications of Microbial Enzymes in Food Industry.Food technology and biotechnology · 2018Review
Corrections and comments
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Authors and funding
7 authors at 2 institutions in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Enzymatic catalysis in microreactors has attracted growing scientific interest because of high specific surface enabling heat and mass transfer and easier control of reaction parameters in microreactors. However, two major challenges that limit their application are fast inactivation and the inability to the biocatalysts in microchannel reactors. A fluid and unsinkable immobilized enzyme were firstly applied in a microchannel reactor for biocatalysis in this study. Functionalized forms of graphene-immobilized naringinase flowing in microchannels have yielded excellent results for isoquercitrin production. A maximum yield of 92.24 ± 3.26% was obtained after 20 min in a microchannel reactor. Ten cycles of enzymatic hydrolysis reaction were successively completed and an enzyme activity above 85.51 ± 2.76% was maintained. The kinetic parameter V
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.