Evidence map›Paper›PMID 28655817›Full record

ArticlemBio2017

Antibody against Microbial Neuraminidases Recognizes Human Sialidase 3 (NEU3): the Neuraminidase/Sialidase Superfamily Revisited.

Chiguang Feng, Jihong Li, Greg Snyder, Wei Huang, Simeon E Goldblum, Wilbur H Chen, Lai-Xi Wang, Bruce A McClane, Alan S Cross

Open access · goldAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in mBio, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed, 1 pooled it
0.4field-weighted citation impact, top 37% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

4 citing papers in PubMed, 1 synthesis or guideline pooled it, 11 citations in OpenAlex.

  1. Pooled it
  2. Review
  3. Article
  4. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors at 2 institutions in 1 country.

Chiguang FengCenter for Vaccine Development, University of Maryland School of Medicine, Baltimore, Maryland, USA.
Jihong LiDepartment of Microbiology and Molecular Genetics, University of Pittsburgh School of Medicine, Pittsburgh, Pennsylvania, USA.
Greg SnyderInstitute of Human Virology and Department of Microbiology and Immunology, University of Maryland School of Medicine, Baltimore, Maryland, USA.
Wei HuangInstitute of Human Virology and Department of Microbiology and Immunology, University of Maryland School of Medicine, Baltimore, Maryland, USA.
Simeon E GoldblumDepartment of Medicine, University of Maryland School of Medicine, Baltimore, Maryland, USA.
Wilbur H ChenCenter for Vaccine Development, University of Maryland School of Medicine, Baltimore, Maryland, USA.ORCID 0000-0001-7741-5536
Lai-Xi WangInstitute of Human Virology and Department of Microbiology and Immunology, University of Maryland School of Medicine, Baltimore, Maryland, USA.
Bruce A McClaneDepartment of Microbiology and Molecular Genetics, University of Pittsburgh School of Medicine, Pittsburgh, Pennsylvania, USA.
Alan S CrossCenter for Vaccine Development, University of Maryland School of Medicine, Baltimore, Maryland, USA across@som.umaryland.edu.
University of Maryland, Baltimore · USUniversity of Pittsburgh · US

Funding

Role of Sialidase in Pulmonary Host Defenses and Acute Lung InjuryR01HL086933 · NHLBI · UNIVERSITY OF MARYLAND BALTIMORE · PI CROSS, ALAN S. · 2007 to 2010
$1.8M
BEHAVIORS AND COGNITIONS FOR RESISTING THE URGE TO SMOKER01NR003145 · NINR · UNIVERSITY OF KANSAS MEDICAL CENTER · PI OCONNELL, KATHLEEN ANN · 1993 to 2003
$1.0M
NHLBI NIH HHS R01 HL086933NINR NIH HHS R01 NR003145
6 · The paper itself

Abstract

Neuraminidases (NAs) are critical virulence factors for several microbial pathogens. With a highly conserved catalytic domain, a microbial NA "superfamily" has been proposed. We previously reported that murine polymorphonuclear leukocyte (PMN) sialidase activity was important in leukocyte trafficking to inflamed sites and that antibodies to

Indexed as

Antibodies, BacterialAntibodies, ViralClostridium perfringensHumansNeuraminidaseViral ProteinsAntibodies, BacterialAntibodies, ViralNA protein, influenza A virusNeu3 protein, humanNeuraminidaseViral Proteinsinflammationinnate immunityNeu3neuraminidasesialidase

Identifiers

PMID28655817
PMCPMC5487728
OpenAlexW2734030221

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.