Evidence map›Paper›PMID 28655767›Full record

ArticleThe Journal of biological chemistry2017

Three distinct 3-methylcytidine (m

Luang Xu, Xinyu Liu, Na Sheng, Kyaw Soe Oo, Junxin Liang, Yok Hian Chionh, Juan Xu, Fuzhou Ye, Yong-Gui Gao, Peter C Dedon and 1 more

Open access · hybridAbstract readComparative Study
In one paragraph

Article in The Journal of biological chemistry, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 137 papers.

0numbers the graph read from it
0cells of the map it votes in
137citing papers in PubMed
7.6field-weighted citation impact, top 2% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

137 citing papers in PubMed, 222 citations in OpenAlex.

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  6. Regulation of RNA-binding proteins by small biomolecules.Nature reviews. Molecular cell biology · 2026
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  18. RNA modifications and their role in gene expression.Frontiers in molecular biosciences · 2025
    Review
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  20. Review

77 more citing papers are in PubMed but not listed here.

4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

11 authors at 7 institutions in 3 countries.

Luang XuFrom the Cancer Science Institute of Singapore, National University of Singapore, 14 Medical Drive, 117599 Singapore.ORCID 0000-0003-2606-0936
Xinyu LiuFrom the Cancer Science Institute of Singapore, National University of Singapore, 14 Medical Drive, 117599 Singapore.
Na Shengthe Model Animal Research Center of Nanjing University, 12 Xuefu Road, 210032 Nanjing, China.
Kyaw Soe OoFrom the Cancer Science Institute of Singapore, National University of Singapore, 14 Medical Drive, 117599 Singapore.
Junxin Liangthe Department of Biochemistry, National University of Singapore, 8 Medical Drive, 117596 Singapore.
Yok Hian Chionhthe Singapore-MIT Alliance for Research and Technology, 1 CREATE Way, 138602 Singapore.
Juan Xuthe Model Animal Research Center of Nanjing University, 12 Xuefu Road, 210032 Nanjing, China.
Fuzhou Yethe School of Biological Sciences, Nanyang Technological University, 60 Nanyang Drive, 637551 Singapore, and.
Yong-Gui Gaothe School of Biological Sciences, Nanyang Technological University, 60 Nanyang Drive, 637551 Singapore, and.
Peter C Dedonthe Singapore-MIT Alliance for Research and Technology, 1 CREATE Way, 138602 Singapore, pcdedon@mit.edu.
Xin-Yuan FuFrom the Cancer Science Institute of Singapore, National University of Singapore, 14 Medical Drive, 117599 Singapore, csifxy@nus.edu.sg.
National University of Singapore · SGNanyang Technological University · SGMassachusetts Institute of Technology · USModel Animal Research Center · CNNanjing University · CNNational University Cancer Institute, Singapore · SGSingapore-MIT Alliance for Research and Technology · SG

Funding

Translational regulation in exposure biology: Xenobiotic-induced reprograming oftRNA modifications and selective translation of codon-biased response genes in rat and humanmodelsR01ES026856 · NIEHS · SUNY POLYTECHNIC INSTITUTE · PI Thomas J Begley, Peter C Dedon · 2016 to 2026
$3.9M
NIEHS NIH HHS R01 ES026856
6 · The paper itself

Abstract

Chemical RNA modifications are central features of epitranscriptomics, highlighted by the discovery of modified ribonucleosides in mRNA and exemplified by the critical roles of RNA modifications in normal physiology and disease. Despite a resurgent interest in these modifications, the biochemistry of 3-methylcytidine (m

Indexed as

RNA Processing, Post-TranscriptionalAnimalsCell LineCytidineHumansIsoenzymesLiverMethylationMethyltransferasesMiceMice, KnockoutMice, Mutant StrainsMutationRecombinant Fusion ProteinsRNA InterferenceRNA, Messenger3-methylcytidineCytidineIsoenzymesMethyltransferasesRecombinant Fusion ProteinsRNA, MessengerRNA, TransferRNA, Transfer, ArgRNA, Transfer, SerRNA, Transfer, ThrSerine-tRNA Ligasehumanm3CMettl2Mettl6Mettl8micemousemRNARNA methyltransferasetransfer RNA (tRNA)

Identifiers

PMID28655767
PMCPMC5582859
OpenAlexW2728379842

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.