Evidence map›Paper›PMID 28655734›Full record

ArticleJournal of the American Heart Association2017

Life's Simple 7 and Incident Heart Failure: The Multi-Ethnic Study of Atherosclerosis.

Oluseye Ogunmoroti, Ebenezer Oni, Erin D Michos, Erica S Spatz, Norrina B Allen, Jamal S Rana, Salim S Virani, Ron Blankstein, Konstantinos N Aronis, Roger S Blumenthal and 4 more

Abstract readMulticenter Study
PubMed Full text at PMC Publisher
In one paragraph

Article in Journal of the American Heart Association, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 68 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
68citing papers in PubMed, 1 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

68 citing papers in PubMed, 1 synthesis or guideline pooled it.

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  19. Preventing new-onset heart failure: Intervening at stage A.American journal of preventive cardiology · 2023
    Review
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8 more citing papers are in PubMed but not listed here.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

14 authors.

Oluseye OgunmorotiCenter for Healthcare Advancement and Outcomes, Baptist Health South Florida, Miami, FL.
Ebenezer OniBrooklyn Hospital Center, Brooklyn, NY.
Erin D MichosCiccarone Center for the Prevention of Heart Disease, Johns Hopkins University, Baltimore, MD.
Erica S SpatzCenter for Outcomes Research and Evaluation, Yale New Haven Hospital, New Haven, CT.
Norrina B AllenDepartment of Preventive Medicine, Feinberg School of Medicine, Northwestern University, Chicago, IL.
Jamal S RanaDivision of Cardiology and Division of Research, Kaiser Permanente Northern California, Oakland, CA.
Salim S ViraniMichael E. DeBakey Veterans Affairs Medical Center, Houston, TX.
Ron BlanksteinDepartments of Medicine and Radiology, Brigham and Women's Hospital, Boston, MA.
Konstantinos N AronisDivision of Cardiology, Department of Medicine, Johns Hopkins Hospital Johns Hopkins University School of Medicine, Baltimore, MD.
Roger S BlumenthalCiccarone Center for the Prevention of Heart Disease, Johns Hopkins University, Baltimore, MD.
Emir VeledarCenter for Healthcare Advancement and Outcomes, Baptist Health South Florida, Miami, FL.
Moyses SzkloDepartment of Epidemiology, Johns Hopkins Bloomberg School of Public Health, Baltimore, MD.
Michael J BlahaCiccarone Center for the Prevention of Heart Disease, Johns Hopkins University, Baltimore, MD.
Khurram NasirCenter for Healthcare Advancement and Outcomes, Baptist Health South Florida, Miami, FL khurramn@baptisthealth.net.

Funding

Yale Clinical and Translational Science Award (U Component)UL1TR001863 · NCATS · YALE UNIVERSITY · PI John H. Krystal, LUCILA OHNO-MACHADO · 2016 to 2026
$102.9M
NCATS NIH HHS UL1 TR001863
6 · The paper itself

Abstract

backgroundThe American Heart Association introduced the Life's Simple 7 (LS7) metrics to assess and promote cardiovascular health. We sought to examine the association between the LS7 metrics and incident heart failure (HF) in a multiethnic cohort. METHODS AND

resultsWe analyzed data from 6506 participants of the Multi-Ethnic Study of Atherosclerosis free of cardiovascular disease at baseline. The LS7 metrics (smoking, physical activity, body mass index, diet, blood pressure, total cholesterol, and blood glucose) were graded on a scale of 0 to 2, with 2 indicating "ideal" status, 1 "intermediate" status, and 0 "poor" status. Points were summed, thus the LS7 score ranged from 0 to 14. Cox proportional hazard ratios and incidence rates of HF per 1000 person-years were calculated. During a median follow-up of 12.2 years, 262 (4%) participants developed HF. Incidence of HF decreased as the number of ideal LS7 metrics increased; 5.9 per 1000 person-years for participants with 0 to 1 ideal metrics and 0.6 per 1000 person-years for those with 6 to 7 ideal metrics. Compared with inadequate scores (0-8 points), hazard ratios for HF were 0.57 (0.43-0.76) and 0.31 (0.19-0.49) for average (9-10 points) and optimal (11-14 points) scores, respectively. A similar pattern was observed when the results were stratified by 4 racial/ethnic groups: white, Chinese American, black, and Hispanic.

conclusionsA lower risk of HF with more favorable LS7 status regardless of race/ethnicity suggests that efforts to achieve ideal cardiovascular health may reduce the burden of HF, a major source of morbidity and mortality.

Indexed as

Healthy LifestyleRisk Reduction BehaviorAgedAged, 80 and overBiomarkersBlood GlucoseBlood PressureBody Mass IndexCholesterolDiet, HealthyExerciseFemaleHeart FailureHumansIncidenceKaplan-Meier EstimateBiomarkersBlood GlucoseCholesterolcardiovascular disease preventionepidemiologyheart failureideal cardiovascular health metricsLife's Simple 7risk factor

Identifiers

PMID28655734
PMCPMC5669160

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.