Evidence map›Paper›PMID 28655524›Full record

ArticleBrazilian journal of otorhinolaryngology

25 (OH) D3 levels, incidence and recurrence of different clinical forms of benig paroxysmal positional vertigo.

Sinisa Maslovara, Silva Butkovic Soldo, Anamarija Sestak, Katarina Milinkovic, Jasna Rogic-Namacinski, Anamarija Soldo

Open access · goldAbstract read
In one paragraph

Article in Brazilian journal of otorhinolaryngology. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 13 papers, 4 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
13citing papers in PubMed, 4 pooled it
2.4field-weighted citation impact, top 11% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

13 citing papers in PubMed, 4 syntheses or guidelines pooled it, 37 citations in OpenAlex.

  1. Pooled it
  2. Pooled it
  3. Pooled it
  4. Association of benign paroxysmal positional vertigo with vitamin D deficiency: a systematic review and meta-analysis.European archives of oto-rhino-laryngology : official journal of the European Federation of Oto-Rhino-Laryngological Societies (EUFOS) : affiliated with the German Society for Oto-Rhino-Laryngology - Head and Neck Surgery · 2018
    Pooled it
  5. Article
  6. Article
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  8. Role of Serum Markers in Benign Paroxysmal Positional Vertigo: Are They Useful?Indian journal of otolaryngology and head and neck surgery : official publication of the Association of Otolaryngologists of India · 2023
    Article
  9. Review
  10. Article
  11. Article
  12. A Relationship Between Blood Levels of Otolin-1 and Vitamin D.Otology & neurotology : official publication of the American Otological Society, American Neurotology Society [and] European Academy of Otology and Neurotology · 2018
    Article
  13. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 2 institutions in 1 country.

Sinisa MaslovaraCounty General Hospital, Department of Otolaryngology, Vukovar, Croatia; University of Osijek, Medical Faculty, Department of Otorhinolaryngology and Maxillofacial Surgery, Osijek, Croatia. Electronic address: sinisamaslovara@yahoo.com.
Silva Butkovic SoldoClinical Hospital Center, Department of Neurology, Osijek, Croatia; University of Osijek, Medical Faculty, Department of Neurology, Osijek, Croatia.
Anamarija SestakCounty General Hospital, Department of Otolaryngology, Vukovar, Croatia.
Katarina MilinkovicCounty General Hospital, Department of Otolaryngology, Vukovar, Croatia.
Jasna Rogic-NamacinskiCounty General Hospital, Department of Otolaryngology, Vukovar, Croatia; County General Hospital, Department of Laboratory Diagnostic, Vukovar, Croatia.
Anamarija SoldoClinical Hospital Center, Department of Neurology, Osijek, Croatia; University of Osijek, Medical Faculty, Department of Neurology, Osijek, Croatia.
Polytechnic Lavoslav Ružička Vukovar · HRUniversity of Osijek · HR

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

introductionBenign paroxysmal positional vertigo is the most common cause of dizziness in the general population. It is a condition with potential impact of reduced levels of vitamin D on its recurrent attacks.

objectivesThe aim of this study was to measure the serum levels of 25-hydroxyvitamin D3 (25-OH D3) in patients with benign paroxysmal positional vertigo and determine whether there is a difference in the serum levels of vitamin D3 between patients with and without recurrence, as well as between the different clinical forms of benign paroxysmal positional vertigo.

methodsThe study included 40 patients who came to the regular medical examination, diagnosed with posterior canal-benign paroxysmal positional vertigo based on the positive Dix-Hallpike's test. All patients underwent Epley manoeuvre after the diagnosis. Patients were classified according to current guidelines for levels of vitamin D3 in the serum in three groups: the deficiency, insufficiency and adequate level.

resultsThe average serum level of 25-OH D3 among respondents was 20.78ng/mL, indicating a lack or insufficiency of the aforementioned 25-OH D3. According to the levels of 25-OH D3, most patients suffer from deficiency (47.5%). 7 (17.5%) respondents had adequate blood level of 25-OH D3, and 14 (35%) respondents suffer from insufficiency. A significant difference was not found in the serum level of 25-OH D3 between patients with and without benign paroxysmal positional vertigo recurrence. There was a significant difference in the serum levels of 25-OH D3 in comparison to the clinical form of the disease. Lower 25-OH D3 values were found in patients with canalithiasis compared to those with cupulolithiasis.

conclusionsThere were no significant differences in the vitamin D3 serum level in patients with and without recurrence. The study showed a low level of serum vitamin D3 in most patients, indicating the need for supplemental therapy.

Indexed as

AgedBenign Paroxysmal Positional VertigoCalcifediolCalciumCholecalciferolFemaleHumansMaleMiddle AgedRecurrenceReference ValuesStatistics, NonparametricVitamin D DeficiencyCalcifediolCalciumCholecalciferolBenign paroxysmal positional vertigoClinical formsFormas clínicasInsuficiência da vitamina D3RecorrênciaRecurrenceVertigem posicional paroxística benignaVitamin D3 insufficiency

Identifiers

PMID28655524
PMCPMC9449225
OpenAlexW2624133814

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.