SynthesisPalliative medicine2018
The costs, resource use and cost-effectiveness of Clinical Nurse Specialist-led interventions for patients with palliative care needs: A systematic review of international evidence.
Synthesis in Palliative medicine, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 28 papers, 5 of them syntheses that pooled it.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
28 citing papers in PubMed, 5 syntheses or guidelines pooled it.
- Updated European Reference Network for rare Inherited and Congenital Digestive and Gastrointestinal Anomalies guidelines for the management of rectosigmoid Hirschsprung's disease 2025.Journal of pediatric gastroenterology and nutrition · 2026Guideline
- Contribution of Clinical Nurses to Hospital Efficiency and Economic Sustainability: A Systematic Review.Journal of nursing management · 2025Pooled it
- Challenges to Systems of Long-Term Care: Mapping of the Central Concepts from an Umbrella Review.International journal of environmental research and public health · 2023Pooled it
- Identifying older adults with frailty approaching end-of-life: A systematic review.Palliative medicine · 2021Pooled it
- Understanding the palliative care needs and experiences of people with mesothelioma and their family carers: An integrative systematic review.Palliative medicine · 2021Pooled it
- Decreased costs and retained QoL due to the 'PACE Steps to Success' intervention in LTCFs: cost-effectiveness analysis of a randomized controlled trial.BMC medicine · 2020Trial
- Costs and cost-effectiveness of palliative care in residential aged care homes: a scoping review.Age and ageing · 2026Article
- Patients' experiences of participating in a nurse-led clinic for bowel dysfunction following rectal cancer: A qualitative interview study.Colorectal disease : the official journal of the Association of Coloproctology of Great Britain and Ireland · 2026Article
- Mapping Competence in Gastrointestinal Endoscopy Nursing Practice: An Item Response Theory Analysis of Perceived Skill Acquisition and Maintenance in Italy.Healthcare (Basel, Switzerland) · 2026Article
- Palliative and end-of-life care from an education lens. An international systematic review of undergraduate medical and nursing students' knowledge, perceptions, and orientation towards palliative and end-of-life care.Palliative care and social practice · 2026Review
- The role and position of palliative care nurses within the Dutch healthcare system: a mixed-methods study.BMC nursing · 2025Article
- Infective endocarditis: it takes a team.European heart journal · 2025Review
- The effectiveness of nurse-led palliative care needs assessment on patients' quality of life and symptom burden: a systematic review.International journal of nursing studies advances · 2025Review
- A longitudinal assessment of factors affecting training transfer among new clinical nurse specialists.International journal of nursing sciences · 2024Article
- A global perspective of advanced practice nursing research: A review of systematic reviews.PloS one · 2024Review
- Development of a patient and clinician co-led education program to promote living well with an implantable cardioverter defibrillator: Insights from a pilot project.PEC innovation · 2022Article
- The implementation of physicians assistant in a surgical ward improves continuity in daily clinical work and increases comprehensibility of nurses and physicians.Patient safety in surgery · 2022Article
- Clinical nurse specialist role in providing generalist and specialist palliative care: A qualitative study of mesothelioma clinical nurse specialists.Journal of advanced nursing · 2022Article
- Guiding the Clinical Nurse Specialist role in oncology within Princess Margaret Cancer Centre.Canadian oncology nursing journal = Revue canadienne de nursing oncologique · 2022Article
- Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
5 authors.
Funding
Abstract
backgroundPatients with palliative care needs do not access specialist palliative care services according to their needs. Clinical Nurse Specialists working across a variety of fields are playing an increasingly important role in the care of such patients, but there is limited knowledge of the extent to which their interventions are cost-effective.
objectivesTo present results from a systematic review of the international evidence on the costs, resource use and cost-effectiveness of Clinical Nurse Specialist-led interventions for patients with palliative care needs, defined as seriously ill patients and those with advanced disease or frailty who are unlikely to be cured, recover or stabilize.
designSystematic review following PRISMA methodology. DATA SOURCES: Medline, Embase, CINAHL and Cochrane Library up to 2015. Studies focusing on the outcomes of Clinical Nurse Specialist interventions for patients with palliative care needs, and including at least one economic outcome, were considered. The quality of studies was assessed using tools from the Joanna Briggs Institute.
resultsA total of 79 papers were included: 37 randomized controlled trials, 22 quasi-experimental studies, 7 service evaluations and other studies, and 13 economic analyses. The studies included a wide variety of interventions including clinical, support and education, as well as care coordination activities. The quality of the studies varied greatly.
conclusionClinical Nurse Specialist interventions may be effective in reducing specific resource use such as hospitalizations/re-hospitalizations/admissions, length of stay and health care costs. There is mixed evidence regarding their cost-effectiveness. Future studies should ensure that Clinical Nurse Specialists' roles and activities are clearly described and evaluated.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.