ArticleMolecular biology and evolution2017
Small RNA Activity in Archeological Barley Shows Novel Germination Inhibition in Response to Environment.
Article in Molecular biology and evolution, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 6 papers, 1 of them a synthesis that pooled it.
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Who cites it
6 citing papers in PubMed, 1 synthesis or guideline pooled it.
- What Do We Know about Barley miRNAs?International journal of molecular sciences · 2022Pooled it
- Herbaria provide a valuable resource for obtaining informative mRNA.Genome research · 2026Article
- An ancient influenza genome from Switzerland allows deeper insights into host adaptation during the 1918 flu pandemic in Europe.BMC biology · 2025Article
- Unraveling the diversity and cultural heritage of fruit crops through paleogenomics.Trends in genetics : TIG · 2024Review
- Ancient RNA from Late Pleistocene permafrost and historical canids shows tissue-specific transcriptome survival.PLoS biology · 2019Article
- Paleogenomics: reconstruction of plant evolutionary trajectories from modern and ancient DNA.Genome biology · 2019Article
Corrections and comments
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Authors and funding
7 authors.
Funding
Abstract
The recovery of ancient RNA from archeological material could enable the direct study of microevolutionary processes. Small RNAs are a rich source of information because their small size is compatible with biomolecular preservation, and their roles in gene regulation make them likely foci of evolutionary change. We present here the small RNA fraction from a sample of archeological barley generated using high-throughput sequencing that has previously been associated with localized adaptation to drought. Its microRNA profile is broadly similar to 19 globally distributed modern barley samples with the exception of three microRNAs (miRNA159, miRNA319, and miR396), all of which are known to have variable expression under stress conditions. We also found retrotransposon activity to be significantly reduced in the archeological barley compared with the controls, where one would expect the opposite under stress conditions. We suggest that the archeological barley's conflicting stress signals could be the result of long-term adaptation to its local environment.
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Registered trials
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