Evidence map›Paper›PMID 28655055›Full record

ArticleJournal of biomedical optics2017

Deep convolutional neural networks for classifying head and neck cancer using hyperspectral imaging.

Martin Halicek, Guolan Lu, James V Little, Xu Wang, Mihir Patel, Christopher C Griffith, Mark W El-Deiry, Amy Y Chen, Baowei Fei

Registry-linked trialAbstract read
In one paragraph

Article in Journal of biomedical optics, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT04589884 (Intraoperative EXamination Using MAChine-learning-based HYperspectral for diagNosis & Autonomous Anatomy Assessment), which is not on this map. Cited by 85 papers, 2 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
85citing papers in PubMed, 2 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT04589884 terminatednot on this mapstarted 2020, after this paper: background citation

Intraoperative EXamination Using MAChine-learning-based HYperspectral for diagNosis & Autonomous Anatomy Assessment

TypeobservationalSponsorIHU StrasbourgRan2020 to 2021Enrolled112ConditionsParathyroid Diseases, Thyroid Diseases, Liver Cancer, Liver MetastasesArmsHyperspectral Imaging
3 · Its place in the literature

Who cites it

85 citing papers in PubMed, 2 syntheses or guidelines pooled it.

  1. Pooled it
  2. Pooled it
  3. Article
  4. Neural illumination calibration for surgical workflow-optimized spectral imaging.International journal of computer assisted radiology and surgery · 2026
    Article
  5. Article
  6. Article
  7. Review
  8. Article
  9. Article
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  12. Optimization of Transfer Learning of Foundation Models for Hyperspectral Histologic Imaging.Proceedings of SPIE--the International Society for Optical Engineering · 2025
    Article
  13. Review
  14. Review
  15. Article
  16. Article
  17. Review
  18. Article
  19. Artificial Intelligence in Medicine and Dentistry.Acta stomatologica Croatica · 2023
    Review
  20. Review

25 more citing papers are in PubMed but not listed here.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors.

Martin HalicekGeorgia Institute of Technology and Emory University, The Wallace H. Coulter Department of Biomedical Engineering, Atlanta, Georgia, United StatesbMedical College of Georgia, Augusta, Georgia, United States.
Guolan LuGeorgia Institute of Technology and Emory University, The Wallace H. Coulter Department of Biomedical Engineering, Atlanta, Georgia, United States.
James V LittleEmory University School of Medicine, Department of Pathology and Laboratory Medicine, Atlanta, Georgia, United States.
Xu WangEmory University School of Medicine, Department of Hematology and Medical Oncology, Atlanta, Georgia, United States.
Mihir PatelEmory University School of Medicine, Department of Otolaryngology, Atlanta, Georgia, United StatesfWinship Cancer Institute of Emory University, Atlanta, Georgia, United States.
Christopher C GriffithEmory University School of Medicine, Department of Pathology and Laboratory Medicine, Atlanta, Georgia, United States.
Mark W El-DeiryEmory University School of Medicine, Department of Otolaryngology, Atlanta, Georgia, United StatesfWinship Cancer Institute of Emory University, Atlanta, Georgia, United States.
Amy Y ChenEmory University School of Medicine, Department of Otolaryngology, Atlanta, Georgia, United StatesfWinship Cancer Institute of Emory University, Atlanta, Georgia, United States.
Baowei FeiGeorgia Institute of Technology and Emory University, The Wallace H. Coulter Department of Biomedical Engineering, Atlanta, Georgia, United StatesfWinship Cancer Institute of Emory University, Atlanta, Georgia, United StatesgEmory University, Department of Radiology and Imaging Sciences, Atlanta, Georgia, United StateshEmory University, Department of Mathematics and Computer Science, Atlanta, Georgia, United States.

Funding

Winship Cancer Institute Cancer Center Support GrantP30CA138292 · NCI · EMORY UNIVERSITY · PI Suresh S Ramalingam · 2009 to 2026
$47.5M
ACADEMIC-INDUSTRIAL PARTNERSHIP FOR TRANSLATION OF PET/TRUS GUIDED INTERVENTIONR01CA204254 · NCI · UNIVERSITY OF TEXAS DALLAS · PI FEI, BAOWEI · 2017 to 2021
$2.0M
MOLECULAR IMAGING DIRECTED, 3D ULTRASOUND-GUIDED, BIOPSY SYSTEMR01CA156775 · NCI · UNIVERSITY OF TEXAS DALLAS · PI FEI, BAOWEI · 2011 to 2016
$1.7M
Targeted fusion biopsy using anti-[18F]FACBC PET/CT and real-time 3D ultrasound gR21CA176684 · NCI · EMORY UNIVERSITY · PI FEI, BAOWEI, MASTER, VIRAJ · 2013 to 2014
$568k
NCI NIH HHS P30 CA138292NCI NIH HHS R01 CA156775NCI NIH HHS R01 CA204254NCI NIH HHS R21 CA176684
6 · The paper itself

Abstract

Surgical cancer resection requires an accurate and timely diagnosis of the cancer margins in order to achieve successful patient remission. Hyperspectral imaging (HSI) has emerged as a useful, noncontact technique for acquiring spectral and optical properties of tissue. A convolutional neural network (CNN) classifier is developed to classify excised, squamous-cell carcinoma, thyroid cancer, and normal head and neck tissue samples using HSI. The CNN classification was validated by the manual annotation of a pathologist specialized in head and neck cancer. The preliminary results of 50 patients indicate the potential of HSI and deep learning for automatic tissue-labeling of surgical specimens of head and neck patients.

Indexed as

Neural Networks, ComputerDiagnostic ImagingHead and Neck NeoplasmsHumans

Identifiers

PMID28655055
PMCPMC5482930

What OpenQuestion holds

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Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.