Evidence map›Paper›PMID 28654473›Full record

ArticlePediatric physical therapy : the official publication of the Section on Pediatrics of the American Physical Therapy Association2017

Regenerative Rehabilitation: Combining Stem Cell Therapies and Activity-Dependent Stimulation.

Chet T Moritz, Fabrisia Ambrosio

Abstract read
In one paragraph

Article in Pediatric physical therapy : the official publication of the Section on Pediatrics of the American Physical Therapy Association, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers.

0numbers the graph read from it
0cells of the map it votes in
5citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

5 citing papers in PubMed.

  1. Review
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  5. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

2 authors.

Chet T MoritzDepartments of Rehabilitation Medicine, Physiology & Biophysics, Electrical Engineering (Dr. Moritz), UW Institute for Neuroengineering, Center for Sensorimotor Neural Engineering, University of Washington School of Medicine, Seattle; and Departments of Physical Medicine & Rehabilitation, Physical Therapy, Bioengineering, and Microbiology & Molecular Genetics (Dr. Ambrosio), McGowan Institute for Regenerative Medicine, University of Pittsburgh, Pennsylvania.
Fabrisia Ambrosio

Funding

VARIABILITY, STABILITY & SMOOTHNESS OF WALKINGP30AG024827 · NIA · UNIVERSITY OF PITTSBURGH AT PITTSBURGH · PI Caterina Rosano · 2004 to 2026
$28.6M
Technology Development P2CHD086843 · NICHD · UNIVERSITY OF PITTSBURGH AT PITTSBURGH · PI AMBROSIO, FABRISIA · 2015 to 2024
$10.5M
NIA NIH HHS P30 AG024827NICHD NIH HHS P2C HD086843
6 · The paper itself

Abstract

The number of clinical trials in regenerative medicine is burgeoning, and stem cell/tissue engineering technologies hold the possibility of becoming the standard of care for a multitude of diseases and injuries. Advances in regenerative biology reveal novel molecular and cellular targets, with potential to optimize tissue healing and functional recovery, thereby refining rehabilitation clinical practice. The purpose of this review is to (1) highlight the potential for synergy between the fields of regenerative medicine and rehabilitation, a convergence of disciplines known as regenerative rehabilitation; (2) provide translational examples of regenerative rehabilitation within the context of neuromuscular injuries and diseases; and (3) offer recommendations for ways to leverage activity dependence via combined therapy and technology, with the goal of enhancing long-term recovery. The potential clinical benefits of regenerative rehabilitation will likely become a critical aspect in the standard of care for many neurological and musculoskeletal disorders.

Indexed as

ExerciseHumansMusculoskeletal DiseasesNervous System DiseasesRegenerative MedicineStem Cell Transplantation

Identifiers

PMID28654473
PMCPMC5488706

What OpenQuestion holds

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Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.