Evidence map›Paper›PMID 28654158›Full record

ArticleBiotechnology and bioengineering2017

An adjustable multi-scale single beam acoustic tweezers based on ultrahigh frequency ultrasonic transducer.

Xiaoyang Chen, Kwok Ho Lam, Ruimin Chen, Zeyu Chen, Ping Yu, Zhongping Chen, K Kirk Shung, Qifa Zhou

Open access · greenAbstract readEvaluation Study
In one paragraph

Article in Biotechnology and bioengineering, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 13 papers.

0numbers the graph read from it
0cells of the map it votes in
13citing papers in PubMed
1.2field-weighted citation impact, top 23% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

13 citing papers in PubMed, 34 citations in OpenAlex.

  1. Acoustic black hole effect enhanced micro-manipulator.Microsystems & nanoengineering · 2024
    Article
  2. Review
  3. Capillary wave tweezer.Scientific reports · 2024
    Article
  4. Article
  5. Article
  6. Article
  7. Manipulation and Mechanical Deformation of Leukemia Cells by High-Frequency Ultrasound Single Beam.IEEE transactions on ultrasonics, ferroelectrics, and frequency control · 2022
    Article
  8. Article
  9. Review
  10. Article
  11. Article
  12. Article
  13. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors at 4 institutions in 3 countries.

Xiaoyang ChenDepartment of Biomedical Engineering, Beckman Laser Institute & Medical Clinic, University of California-Irvine, Irvine, California.ORCID 0000-0002-1098-8185
Kwok Ho LamDepartment of Electrical Engineering, The Hong Kong Polytechnic University, Hunghom, Kowloon, Hong Kong.
Ruimin ChenDepartment of Biomedical Engineering and NIH Transducer Resource Center, University of Southern California, Los Angeles, California 90089.
Zeyu ChenDepartment of Biomedical Engineering and NIH Transducer Resource Center, University of Southern California, Los Angeles, California 90089.
Ping YuCollege of Material Science and Engineering, Sichuan University, Chengdu, People's Republic of China.
Zhongping ChenDepartment of Biomedical Engineering, Beckman Laser Institute & Medical Clinic, University of California-Irvine, Irvine, California.
K Kirk ShungDepartment of Biomedical Engineering and NIH Transducer Resource Center, University of Southern California, Los Angeles, California 90089.
Qifa ZhouDepartment of Biomedical Engineering and NIH Transducer Resource Center, University of Southern California, Los Angeles, California 90089.
University of Southern California · USHong Kong Polytechnic University · HKSichuan University · CNUniversity of California, Irvine · US

Funding

A Resource on Medical Ultrasonic Transducer TechnologyP41EB002182 · NIBIB · UNIVERSITY OF SOUTHERN CALIFORNIA · PI SHUNG, K KIRK · 2003 to 2016
$13.3M
Acoustic Trapping of Small Biological ParticlesR01EB012058 · NIBIB · UNIVERSITY OF SOUTHERN CALIFORNIA · PI SHUNG, K KIRK · 2010 to 2013
$2.3M
NIBIB NIH HHS P41 EB002182NIBIB NIH HHS R01 EB012058
6 · The paper itself

Abstract

This paper reports the fabrication, characterization, and microparticle manipulation capability of an adjustable multi-scale single beam acoustic tweezers (SBAT) that is capable of flexibly changing the size of "tweezers" like ordinary metal tweezers with a single-element ultrahigh frequency (UHF) ultrasonic transducer. The measured resonant frequency of the developed transducer at 526 MHz is the highest frequency of piezoelectric single crystal based ultrasonic transducers ever reported. This focused UHF ultrasonic transducer exhibits a wide bandwidth (95.5% at -10 dB) due to high attenuation of high-frequency ultrasound wave, which allows the SBAT effectively excite with a wide range of excitation frequency from 150 to 400 MHz by using the "piezoelectric actuator" model. Through controlling the excitation frequency, the wavelength of ultrasound emitted from the SBAT can be changed to selectively manipulate a single microparticle of different sizes (3-100 μm) by using only one transducer. This concept of flexibly changing "tweezers" size is firstly introduced into the study of SBAT. At the same time, it was found that this incident ultrasound wavelength play an important role in lateral trapping and manipulation for microparticle of different sizes. Biotechnol. Bioeng. 2017;114: 2637-2647. © 2017 Wiley Periodicals, Inc.

Indexed as

TransducersAcousticsCell SeparationEquipment DesignEquipment Failure AnalysisMicromanipulationReproducibility of ResultsSensitivity and SpecificityUltrasonographyacoustic trappingadjustable multi-scale tweezersmicroparticle trapping and manipulation“piezoelectric actuator” modelultrahigh frequency ultrasonic transducer

Identifiers

PMID28654158
PMCPMC10309180
OpenAlexW2727988104

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.