Exploitation of SPR to Investigate the Importance of Glycan Chains in the Interaction between Lactoferrin and Bacteria.

Noelle O'Riordan, Michelle Kilcoyne, Lokesh Joshi, Rita M Hickey

Open access · goldAbstract read

In one paragraph

Article in Sensors (Basel, Switzerland), 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it

0cells of the map it votes in

1citing papers in PubMed

0.3field-weighted citation impact, top 38% of its field

1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed, 4 citations in OpenAlex.

The Role of Glycans in Bacterial Adhesion to Mucosal Surfaces: How Can Single-Molecule Techniques Advance Our Understanding?Microorganisms · 2018
Review

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors at 2 institutions in 1 country.

Noelle O'RiordanBiosciences Department, Teagasc Food Research Centre, Moorepark, Fermoy, P61C996 Co. Cork, Ireland. noriordan1@gmail.com.

Michelle KilcoyneGlycoscience Group, National Centre for Biomedical Engineering Science, National University of Ireland Galway, H91TK33, Galway, Ireland. michelle.kilcoyne@nuigalway.ie.

Lokesh JoshiGlycoscience Group, National Centre for Biomedical Engineering Science, National University of Ireland Galway, H91TK33, Galway, Ireland. lokesh.joshi@nuigalway.ie.

Rita M HickeyBiosciences Department, Teagasc Food Research Centre, Moorepark, Fermoy, P61C996 Co. Cork, Ireland. rita.hickey@teagasc.ie.

Ollscoil na Gaillimhe – University of Galway · IETeagasc - The Irish Agriculture and Food Development Authority · IE

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Bovine lactoferrin (LF) has been shown to prevent adhesion to and invasion of mammalian cell lines by pathogenic bacteria, with evidence for direct bacterial binding by the milk glycoprotein. However, the glycosylation pattern of LF changes over the lactation cycle. In this study, we aim to investigate the effect that this variation has on the milk glycoprotein's ability to interact with pathogens. Surface plasmon resonance technology was employed to compare the binding of LF from colostrum (early lactation) and mature milk (late lactation) to a panel of pathogenic bacteria (

Indexed as

BacteriaAnimalsMilkPolysaccharidesStaphylococcus aureusSurface Plasmon ResonancePolysaccharidesbacterial bindingglycosylationlactationlactoferrinsurface plasmon resonance

Identifiers

PMID28653977

DOI10.3390/s17071515

PMCPMC5539864

OpenAlexW2641503062

What OpenQuestion holds

Textmetadata

LicenceCC BY

Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.